Microglia activation is essential for BMP7-mediated retinal reactive gliosis

Simple item page
dc.contributor.authorDharmarajan, Subramanian
dc.contributor.authorFisk, Debra L.
dc.contributor.authorSorenson, Christine M.
dc.contributor.authorSheibani, Nader
dc.contributor.authorBelecky-Adams, Teri L.
dc.contributor.departmentDepartment of Biology, School of Scienceen_US
dc.date.accessioned2017-05-01T19:22:21Z
dc.date.available2017-05-01T19:22:21Z
dc.date.issued2017
dc.description.abstractOur previous studies have shown that BMP7 is able to trigger activation of retinal macroglia. However, these studies showed the responsiveness of Müller glial cells and retinal astrocytes in vitro was attenuated in comparison to those in vivo, indicating other retinal cell types may be mediating the response of the macroglial cells to BMP7. In this study, we test the hypothesis that BMP7-mediated gliosis is the result of inflammatory signaling from retinal microglia.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationDharmarajan, S., Fisk, D. L., Sorenson, C. M., Sheibani, N., & Belecky-Adams, T. L. (2017). Microglia activation is essential for BMP7-mediated retinal reactive gliosis. Journal of Neuroinflammation, 14, 76. https://doi.org/10.1186/s12974-017-0855-0en_US
dc.identifier.issn1742-2094en_US
dc.identifier.urihttps://hdl.handle.net/1805/12389
dc.language.isoen_USen_US
dc.publisherBioMed Centralen_US
dc.relation.isversionof10.1186/s12974-017-0855-0en_US
dc.relation.journalJournal of Neuroinflammationen_US
dc.rightsAttribution 3.0 United States
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/
dc.sourcePublisheren_US
dc.subjectBMP7en_US
dc.subjectMicrogliaen_US
dc.subjectMüller gliaen_US
dc.subjectReactive gliosisen_US
dc.subjectRetinaen_US
dc.subjectRetinal astrocytesen_US
dc.titleMicroglia activation is essential for BMP7-mediated retinal reactive gliosisen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
art%3A10.1186%2Fs12974-017-0855-0.pdf
Size:
6.71 MB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.88 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Open Access Policy Articles
Department of Biology Works
Open Access Publishing Fund