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ILL 101: ILL Basics and Panel Q & A
(2024-10-11) Kennedy, Maureen; Moseman, Holli; Tomberlin, Cetoria
Presentation of the basics of ILL services, including borrowing, lending, document delivery, on demand and international issues. Plus a 20 minute panel Q & A with 3 ILL professionals who have a total of 55 years of experience.
Conference website: https://library.ivytech.edu/D2D2024
A randomized controlled trial assessing denture adhesive efficacy on denture retention across 13 hours
(Wiley, 2024-04) Klukowska, Malgorzata; Grender, Julie; Gossweiler, Ana; Biomedical and Applied Sciences, School of Dentistry
Purpose
To compare the effects of two denture adhesive formulations on the bite force required to dislodge a maxillary denture in adult participants during a 13-h test period.
Materials and Methods
Twenty-two participants with a fair-to-poor fitting maxillary denture opposed by natural dentition or a stable mandibular denture were enrolled in this single-center, randomized, double-blind, two-treatment, 4-period crossover study. Participants were randomly assigned a product usage sequence so that each participant used each product twice during the 4-day test period. The test product was a denture cream adhesive formulated with an optimized calcium/zinc partial salt of polyvinyl methyl ether/maleic acid (Fixodent Ultra technology); the control product was a cream adhesive formulated with a calcium/zinc partial salt of polyvinyl methyl ether/maleic acid (Fixodent Original technology). On each study day, bite force at dislodgement was measured with a gnathodynamometer at baseline, representing the “no adhesive” score. Then, after standardized product application to the participant's existing maxillary denture by site staff, bite force measurements were retaken at 1, 3, 5, 7, 9, 11, and 13 h. The change from baseline and the 13-h area under the bite-force–change-from-baseline curve were analyzed via an analysis of variance.
Results
Twenty-one participants completed all test periods; one additional participant completed three test periods so 22 participants were included in the analysis. There were 15 females and 7 males with a mean age of 70 years. The mean 13-h area under the bite-force–change-from-baseline curve was 8% greater (p = 0.010) for the test adhesive (114.3 lb) than for the control adhesive (105.9 lb). Both adhesives showed a statistically significant increase in bite force (p < 0.001) at each time point compared to no adhesive.
Conclusions
The optimized calcium/zinc partial salt of polyvinyl methyl ether/maleic acid test adhesive provided superior maxillary denture retention relative to that of the control adhesive across 13 h. Both adhesives increased bite force at dislodgement compared to no adhesive.
Short-term beetroot juice supplementation improves muscle speed and power but does not reduce blood pressure or oxidative stress in 65–79 y old men and women
(Elsevier, 2023-09) Zoughaib, William S.; Hoffman, Richard L.; Yates, Brandon A.; Moorthi, Ranjani N.; Lim, Kenneth; Coggan, Andrew R.; Exercise & Kinesiology, School of Health and Human Sciences
We have previously demonstrated that acute ingestion of inorganic nitrate (NO3−)-rich beetroot juice (BRJ), a source of nitric oxide (NO) via the NO3− → nitrite (NO2−) → NO pathway, can improve muscle speed and power in older individuals. It is not known, however, whether this effect is maintained or perhaps even enhanced with repeated ingestion, or if tolerance develops as with organic nitrates, e.g., nitroglycerin. Using a double-blind, placebo-controlled, crossover design, we therefore studied 16 community-dwelling older (age 71 ± 5 y) individuals after both acute and short-term (i.e., daily for 2 wk) BRJ supplementation. Blood samples were drawn and blood pressure was measured periodically during each ∼3 h experiment, with muscle function determined using isokinetic dynamometry. Acute ingestion of BRJ containing 18.2 ± 6.2 mmol of NO3− increased plasma NO3− and NO2− concentrations 23 ± 11 and 2.7 ± 2.1-fold over placebo, respectively. This was accompanied by 5 ± 11% and 7 ± 13% increases in maximal knee extensor speed (Vmax) and power (Pmax), respectively. After daily supplementation for 2 wk, BRJ ingestion elevated NO3− and NO2− levels 24 ± 12 and 3.3 ± 4.0-fold, respectively, whereas Vmax and Pmax were 7 ± 9% and 9 ± 11% higher than baseline. No changes were observed in blood pressure or in plasma markers of oxidative stress with either acute or short-term NO3− supplementation. We conclude that both acute and short-term dietary NO3− supplementation result in similar improvements in muscle function in older individuals. The magnitudes of these improvements are sufficient to offset the decline resulting from a decade or more of aging and are therefore likely to be clinically significant.
Examining the emergence of a learning collaborative: a framework to support complex program implementation
(Springer Nature, 2024-04) Karikari, Isaac; Walton, Betty; Ludeker-Seibert, Kristen; Riley, Kathy; School of Social Work
To address unmet behavioral health needs of children and youth, the system of care (SOC) philosophy was developed and evolved into a framework to support community-based coordinated networks that provide an array of effective services and supports. There is limited elaboration of the actual implementation processes and intricacies of SOC development, particularly, in terms of the roles of local SOC coordinators (local coordinators). Limited published research has addressed the necessary knowledge and roles of local coordinators, and the theoretical underpinnings and structure of their learning, skill development, and capacity building. Utilizing an archival approach and reflexive thematic analysis, this qualitative study examined records of three forums involving 50 local SOC coordinators (11% male, 89% female, 93% white, ages between 27 and 66 years) between 2017 and 2018. The analysis revealed varying levels of experience, knowledge, and skills, and uncovered several SOC development strategies utilized by coordinators. The study illustrates the inception of a learning collaborative that served as a bridge and implementation driver for SOC development and socio-professional support for local coordinators. The findings provide an empirical base and emerging framework for SOC coordinators’ training and professional development. The value of learning collaboratives in facilitating exposure to a diverse knowledge base and the importance of fostering supportive spaces for coordinators as they strive to develop SOCs are evident. Incorporating supportive learning collaboratives for local change agents could be a dynamic strategy to support the effective implementation of system-wide changes or enhancements in behavioral health services.
Correction: Nelson et al. UGT1A1 Guided Cancer Therapy: Review of the Evidence and Considerations for Clinical Implementation. Cancers 2021, 13, 1566
(MDPI, 2024-10-25) Nelson, Ryan S.; Seligson, Nathan D.; Bottiglieri, Sal; Carballido, Estrella; Del Cueto, Alex; Imanirad, Iman; Levine, Richard; Parker, Alexander S.; Swain, Sandra M.; Tillman, Emma M.; Hicks, J. Kevin; Pharmacology and Toxicology, School of Medicine