A new Down syndrome rat model races forward
| dc.contributor.author | Roper, Randall J. | |
| dc.contributor.author | Goodlett, Charles R. | |
| dc.contributor.department | Biology, School of Science | |
| dc.date.accessioned | 2024-04-11T13:23:36Z | |
| dc.date.available | 2024-04-11T13:23:36Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Animal models of Down syndrome (DS) provide an essential resource for understanding genetic, cellular, and molecular contributions to traits associated with trisomy 21 (Ts21). Recent genetic enhancements in the development of DS models, including the new TcHSA21rat model (Kazuki et al.), have potential to transform our understanding of and potential therapies for Ts21. | |
| dc.eprint.version | Author's manuscript | |
| dc.identifier.citation | Roper RJ, Goodlett CR. A new Down syndrome rat model races forward. Trends Genet. 2022;38(11):1101-1102. doi:10.1016/j.tig.2022.05.001 | |
| dc.identifier.uri | https://hdl.handle.net/1805/39915 | |
| dc.language.iso | en_US | |
| dc.publisher | Elsevier | |
| dc.relation.isversionof | 10.1016/j.tig.2022.05.001 | |
| dc.relation.journal | Trends in Genetics | |
| dc.rights | Publisher Policy | |
| dc.source | PMC | |
| dc.subject | Trisomy | |
| dc.subject | Animal models | |
| dc.subject | Gene dosage | |
| dc.subject | Neurodevelopment | |
| dc.subject | Gene expression | |
| dc.title | A new Down syndrome rat model races forward | |
| dc.type | Article |