Robust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage.

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dc.contributor.authorSridhar, Akshayalakshmi
dc.contributor.authorOhlemacher, Sarah K.
dc.contributor.authorLanger, Kirstin B.
dc.contributor.authorMeyer, Jason S.
dc.contributor.departmentDepartment of Biology, School of Scienceen_US
dc.date.accessioned2016-12-21T20:26:11Z
dc.date.available2016-12-21T20:26:11Z
dc.date.issued2016-04
dc.description.abstractThe ability and efficiency of mRNA-reprogrammed human induced pluripotent stem cells (hiPSCs) to yield retinal cell types in a directed, stepwise manner was tested. hiPSCs derived through mRNA-based reprogramming strategies offer numerous advantages owing to the lack of genomic integration or constitutive expression of pluripotency genes. Such methods represent a promising new approach for retinal stem cell research, especially translational applications.en_US
dc.eprint.versionPublished versionen_US
dc.identifier.citationSridhar, A., Ohlemacher, S. K., Langer, K. B., & Meyer, J. S. (2016). Robust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage. Stem Cells Translational Medicine, 5(4), 417–426. https://doi.org/10.5966/sctm.2015-0093en_US
dc.identifier.issn2157-6564 2157-6580en_US
dc.identifier.urihttps://hdl.handle.net/1805/11697
dc.language.isoen_USen_US
dc.publisherAlphaMed Pressen_US
dc.relation.isversionof10.5966/sctm.2015-0093en_US
dc.relation.journalStem Cells Translational Medicineen_US
dc.rightsPublisher's Policyen_US
dc.sourcePMCen_US
dc.subjectDifferentiationen_US
dc.subjectInduced pluripotent stem cellen_US
dc.subjectReprogrammingen_US
dc.subjectRetinaen_US
dc.titleRobust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage.en_US
dc.typeArticleen_US
ul.alternative.fulltexthttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798730/en_US
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