Robust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage.
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2016-04
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American English
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AlphaMed Press
Abstract
The ability and efficiency of mRNA-reprogrammed human induced pluripotent stem cells (hiPSCs) to yield retinal cell types in a directed, stepwise manner was tested. hiPSCs derived through mRNA-based reprogramming strategies offer numerous advantages owing to the lack of genomic integration or constitutive expression of pluripotency genes. Such methods represent a promising new approach for retinal stem cell research, especially translational applications.
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Sridhar, A., Ohlemacher, S. K., Langer, K. B., & Meyer, J. S. (2016). Robust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage. Stem Cells Translational Medicine, 5(4), 417–426. https://doi.org/10.5966/sctm.2015-0093
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2157-6564 2157-6580
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Stem Cells Translational Medicine
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PMC
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Article
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Published version