Ruth Lilly Medical Library works

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184 Cross-institutional collaborations for health equity research at a CTSA
(Cambridge University Press, 2022-04-19) Whipple, Elizabeth C.; Ramirez, Mirian; Dolan, Levi; Hunt, Joe D.; Ruth Lilly Medical Library, School of Medicine
OBJECTIVES/GOALS: We were interested in health equity research for each CTSA-affiliated institution, specifically focusing on cross department and cross-campus co-authorship. We conducted a bibliometric analysis of our CTSA-funded papers relating to diversity and inclusion to identify cross department and cross-campus collaborations. METHODS/STUDY POPULATION: We worked with our CTSAs Racial Justice, Diversity, Equity and Inclusion Task Force to conduct an environmental scan of diversity and inclusion research across our CTSA partner institutions. Using the Scopus database, searches were constructed to identify and retrieve the variety of affiliations for each of the CTSA authors, a health equity/health disparities search hedge, and all of our CTSA grant numbers. We limited the dates from the beginning of our CTSA in 2008-November 2021. We used PubMed to retrieve all MeSH terms for the articles. We used Excel to analyze the data, Python and NCBIs Entrez Programming Utilities to analyze MeSH terms, and VOSviewer to produce the visualizations. RESULTS/ANTICIPATED RESULTS: The results of this search yielded 94 articles overall. We broke these up into subsets (not mutually exclusive) to represent five of the researcher groups across our CTSA. We analyzed the overall dataset for citation count, normalized citation count, CTSA average authors, gender trends, and co-term analysis. We also developed cross department co-authorship maps and cross-institutional/group co-authorship maps. DISCUSSION/SIGNIFICANCE: This poster will demonstrate both the current areas where cross-departmental and cross-institutional collaboration exists among our CTSA authors, as well as identify potential existing areas for collaboration to occur. These findings may determine areas our CTSA can support to improve institutional performance in addressing health equity.
A scoping review of librarian involvement in competency-based medical education
(University Library System at the University of Pittsburgh, 2025) Cyrus, John W.; Zeigen, Laura; Knapp, Molly; Blevins, Amy E.; Patterson, Brandon; Ruth Lilly Medical Library, School of Medicine
Objective: A scoping review was undertaken to understand the extent of literature on librarian involvement in competency-based medical education (CBME). Methods: We followed Joanna Briggs Institute methodology and PRISMA-ScR reporting guidelines. A search of peer-reviewed literature was conducted on December 31, 2022, in Medline, Embase, ERIC, CINAHL Complete, SCOPUS, LISS, LLIS, and LISTA. Studies were included if they described librarian involvement in the planning, delivery, or assessment of CBME in an LCME-accredited medical school and were published in English. Outcomes included characteristics of the inventions (duration, librarian role, content covered) and of the outcomes and measures (level on Kirkpatrick Model of Training Evaluation, direction of findings, measure used). Results: Fifty studies were included of 11,051 screened: 46 empirical studies or program evaluations and four literature reviews. Studies were published in eight journals with two-thirds published after 2010. Duration of the intervention ranged from 30 minutes to a semester long. Librarians served as collaborators, leaders, curriculum designers, and evaluators. Studies primarily covered asking clinical questions and finding information and most often assessed reaction or learning outcomes. Conclusions: A solid base of literature on librarian involvement in CBME exists; however, few studies measure user behavior or use validated outcomes measures. When librarians are communicating their value to stakeholders, having evidence for the contributions of librarians is essential. Existing publications may not capture the extent of work done in this area. Additional research is needed to quantify the impact of librarian involvement in competency-based medical education.
AARC and PALISI Clinical Practice Guideline: Pediatric Critical Asthma
(Mary Ann Liebert, Inc., 2025) White, Benjamin R.; Miller, Andrew G.; Baker, Joyce; Basnet, Sangita; Carroll, Christopher L.; Craven, Hannah J.; Dalabih, Abdallah; Fitzpatrick, Anne M.; Glogowski, Joel; Irazuzta, Jose Enrique; Kapuscinski, Christine A.; Lenox, Jesslyn; Lovinsky-Desir, Stephanie; Maue, Danielle K.; Moody, Gerald; Newth, Christopher; Rehder, Kyle J.; Sochet, Anthony A.; Said, Sana J.; Willis, L. Denise; Whipple, Elizabeth C.; Goodfellow, Lynda; Abu-Sultaneh, Samer
To address the lack of guidance for clinicians in their care of children with critical asthma, a multidisciplinary team of medical providers used Grading of Recommendations, Assessment, Development, and Evaluation methodology to make the following recommendations: 1. We suggest the use of continuous inhaled short-acting β agonist (SABA) over frequent intermittent SABA in children treated for critical asthma. (Conditional recommendation, very low certainty of evidence) 2. We suggest the use of either high- or low-dose continuous inhaled SABA regimens in children treated for critical asthma. (Conditional recommendation, very low certainty of evidence) 3. We suggest the use of either dexamethasone or methylprednisolone (or an equivalent dose of prednisone/prednisolone) for children treated for critical asthma. (Conditional recommendation, very low certainty of evidence) 4. We suggest the use of intravenous (IV) magnesium (intermittent or continuous) as an adjunct therapy in children treated for critical asthma. (Conditional recommendation, low certainty of evidence) 5. We cannot recommend for or against the use of IV methylxanthines as an adjunct therapy in children treated for critical asthma. (Conditional recommendation, very low certainty of evidence) 6. We suggest the use of an IV SABA infusion as an adjunct therapy in children treated for critical asthma. (Conditional recommendation, low certainty of evidence) 7. We cannot recommend for or against the application of high-flow nasal cannula versus conventional oxygen therapy in children presenting with critical asthma with persistent hypoxemia and/or respiratory distress. (Conditional recommendation, very low certainty of evidence) 8. We suggest the use of bi-level positive airway pressure over conventional oxygen therapy in children presenting with critical asthma with persistent hypoxemia and/or respiratory distress. (Conditional recommendation, very low certainty of evidence) 9. We cannot recommend for or against the application of bi-level positive airway pressure over high-flow nasal cannula for children hospitalized with critical asthma with persistent hypoxemia and/or respiratory distress. (Conditional recommendation, very low certainty of evidence) 10. We cannot recommend for or against the application of heliox in children treated for critical asthma. (Conditional recommendation, very low certainty of evidence) 11. We suggest the use of a dedicated protocol or pathway for managing children treated for critical asthma. (Conditional recommendation, low certainty of evidence).
Accessibility assessment of the Midwest Chapter of MLA
(2024-10-11) Pionke, JJ; Biszaha, Anna; Chrisagis, Ximena; DeCaro, Jessica; Feldman, Jennifer; Natal, Gerald; Regan, Matt; Gilbert Redman, Jessica D.; Shannon, Carol; Stumpff, Julia C.; Westall, Sara
In 2023, JJ Pionke became the President of the Midwest Chapter of the Medical Library Association. He determined that for his presidential year, he would form a task force to determine the accessibility of the Chapter and remediate accessibility issues as appropriate. Case Presentation: To accomplish the accessibility audit of the organization, Pionke formed an Accessibility Task Force that was time limited to one year. Task force meetings were held once a month to keep people accountable and to share out progress and requests for assistance. The task force was broken up into four teams: annual meeting, policy, social media, and website. Task force members could be on more than one team. The goals of each team were generally the same: what are other organizations doing, what do we have already if anything, and develop best practices/policy/etc. as needed. Conclusions: The teams fulfilled their mandate by creating best practices/guidelines/policies documents. Some accessibility remediation was needed for the chapter website. The task force’s findings and materials were shared out among the Chapter as well as passed on to other Chapters, many of whom had expressed interest in our results.
Amy Blevins, Medical Library Association President, 2023–2024
(University Library System at the University of Pittsburgh, 2025) Kiscaden, Elizabeth; Craven, Hannah J.; Rios, Gabriel R.; Harris, Ryan; Nicholson, Joey; Ruth Lilly Medical Library, School of Medicine
Amy Blevins served as the Medical Library Association president from 2023-2024. In this presidential biography, the authors outline a history of Blevins' recruitment to the career, career development, and impact on the association and the profession.
Analysis of Public Preprint Server Comments on NIH Preprint Pilot Articles
(2022-05-04) Sawyer, Amanda; Cruise, Allison; Dolan, Levi; Chatmon, Brianna
Objectives: Given the increased prevalence of preprints during the COVID-19 pandemic, this project sought to analyze public comments left on a sample of preprint articles from the NIH Preprint Pilot to determine if they were substantive in nature. Analysis of article titles and qualitative coding of the comments was conducted. This analysis was designed to obtain both quantitative and qualitative measures of comments on a selected group of articles so that the relationship between public commenting and scientific rigor could be explored. Methods: The first 1,000 preprint articles to be indexed in PubMed Central and hosted on two preprint platforms (bioRxiv and medRxiv) were selected. Using the preprint servers’ associated commenting platforms, full text comment threads and Twitter information was obtained, and summary statistics of commenting platforms were produced. From the article sample a total of 494 comments were collected from public commenters using the Disqus platform to provide feedback on the articles. Using the article titles, the authors explored indications of the relationship between article topic and frequency of commenter engagement. Preliminary coding was conducted using a ‘thumbs up/thumbs down’ method and potential categorizations were suggested. Utilizing these suggestions, the authors created and refined a draft codebook. Finally, thirteen categorizations, ten for substantive comments and three for not substantive comments, were created and used to qualitatively code the comment sample. Results: Two rounds of coding were completed to reach sufficient interrater reliability. The authors found that most of the public comments were substantive, with over 28% meeting the criteria for critique, 21.5% as questions for authors, and over 11% having aspects of a formal peer review process. The analysis revealed engagement between commenters and preprint authors, demonstrated through author responses to questions, updates, and feedback. Commenters also provided suggestions for future research (3.6%) and indicated their intent to utilize the preprint findings in future research projects of their own (2.6%). Conclusions: This project provides evidence of the impact of public commenting on scientific rigor. Public commenting was frequently substantive, and provided critique which sometimes led to direct revisions of the preprint article. Commenters also provided responses similar in nature to the formal peer review process, providing authors with feedback faster than the traditional process. Through preprints authors can disseminate their research to a wide audience earlier, and comments indicated that some readers intended to use the preprint findings in their own research, accelerating the potential for scientific discovery. As the prevalence of preprints continues to grow and public engagement with preprints increases, this paper’s methodology can be replicated and refined to further analyze the value of public commenting on preprints.
Asking Data Analysis Questions with PandasAI
(2023-11-08) Dolan, Levi
As easily accessible AI models have increased in visibility, one area of interest for those working with datasets programmatically is how AI might streamline common data analysis tasks. The recently-released PandasAI library is a Python library that connects to an OpenAI model (known for ChatGPT) and allows users to ask natural language-style questions about dataframes created in Pandas syntax. This lightning talk demonstrates how to start exploring this data analysis method using sample World Bank and World Happiness Report data. Potential limitations are also discussed.
Assessment of Service Desk Quality at an Academic Health Sciences Library
(Taylor & Francis, 2016) Blevins, Amy E.; DeBerg, Jen; Kiscaden, Elizabeth; Ruth Lilly Medical Library
Due to an identified need for formal assessment, a small team of librarians designed and administered a survey to gauge the quality of customer service at their academic health sciences library. Though results did not drive major changes to services, several important improvements were implemented and a process was established to serve as a foundation for future use. This article details the assessment process used and lessons learned during the project.
Association of Checklist Use in Endotracheal Intubation With Clinically Important Outcomes: A Systematic Review and Meta-analysis
(American Medical Association, 2020-07-01) Turner, Joseph S.; Bucca, Antonino W.; Propst, Steven L.; Ellender, Timothy J.; Sarmiento, Elisa J.; Menard, Laura M.; Hunter, Benton R.; Emergency Medicine, School of Medicine
Importance: The ε4 allele of the apolipoprotein E (APOE) gene and lower apolipoprotein E (apoE) protein levels in plasma are risk factors for Alzheimer disease, but the underlying biological mechanisms are not fully understood. Half of plasma apoE circulates on high-density lipoproteins (HDLs). Higher apoE levels in plasma HDL were previously found to be associated with lower coronary heart disease risk, but the coexistence of another apolipoprotein, apoC3, modified this lower risk. Objective: To investigate associations between the presence of apoE in different lipoproteins with cognitive function, particularly the risk of dementia. Design, Setting, and Participants: This prospective case-cohort study embedded in the Ginkgo Evaluation of Memory Study (2000-2008) analyzed data from 1351 community-dwelling participants 74 years and older. Of this group, 995 participants were free of dementia at baseline (recruited from September 2000 to June 2002) and 521 participants were diagnosed with incident dementia during follow-up until 2008. Data analysis was performed from January 2018 to December 2019. Exposures: Enzyme-linked immunosorbent assay–measured concentration of apoE in whole plasma, HDL-depleted plasma (non-HDL), HDL, and HDL subspecies that contain or lack apoC3 or apoJ. Main Outcomes and Measures: Adjusted hazard ratios for risk of dementia and Alzheimer disease during follow-up and adjusted differences (β coefficients) in Alzheimer Disease Assessment–Cognitive Subscale (ADAS-cog) and Modified Mini-Mental State Examination scores at baseline. Results: Among 1351 participants, the median (interquartile range) age was 78 (76-81) years; 639 (47.3%) were women. The median (interquartile range) follow-up time was 5.9 (3.7-6.5) years. Higher whole plasma apoE levels and higher apoE levels in HDL were associated with better cognitive function assessed by ADAS-cog (whole plasma, β coefficient, −0.15; 95% CI, −0.24 to −0.06; HDL, β coefficient, −0.20; 95% CI, −0.30 to −0.10) but were unassociated with dementia or Alzheimer disease risk. When separated by apoC3, a higher apoE level in HDL that lacks apoC3 was associated with better cognitive function (ADAS-cog per SD: β coefficient, 0.17; 95% CI, −0.27 to −0.07; Modified Mini-Mental State Examination score per SD: β coefficient, 0.25; 95% CI, 0.07 to 0.42) and lower risk of dementia (hazard ratio per SD, 0.86; 95% CI, 0.76 to 0.99). In contrast, apoE levels in HDL that contains apoC3 were unassociated with any of these outcomes. Conclusions and Relevance: In a prospective cohort of older adults with rigorous follow-up of dementia, the apoE level in HDL that lacked apoC3 was associated with better cognitive function and lower dementia risk. This finding suggests that the cardioprotective associations of this novel lipoprotein extend to dementia.
Association of Extubation Failure Rates With High-Flow Nasal Cannula, Continuous Positive Airway Pressure, and Bilevel Positive Airway Pressure vs Conventional Oxygen Therapy in Infants and Young Children: A Systematic Review and Network Meta-Analysis
(American Medical Association, 2023-06-05) Iyer, Narayan Prabhu; Rotta, Alexandre T.; Essouri, Sandrine; Fioretto, Jose Roberto; Craven, Hannah J.; Whipple, Elizabeth C.; Ramnarayan, Padmanabhan; Abu-Sultaneh, Samer; Khemani, Robinder G.
IMPORTANCE: Extubation failure (EF) has been associated with worse outcomes in critically ill children. The relative efficacy of different modes of noninvasive respiratory support (NRS) to prevent EF is unknown. OBJECTIVE: To study the reported relative efficacy of different modes of NRS (high-flow nasal cannula [HFNC], continuous positive airway pressure [CPAP], and bilevel positive airway pressure [BiPAP]) compared to conventional oxygen therapy (COT). DATA SOURCES: MEDLINE, Embase, and CINAHL Complete through May 2022. STUDY SELECTION: Randomized clinical trials that enrolled critically ill children receiving invasive mechanical ventilation for more than 24 hours and compared the efficacy of different modes of postextubation NRS. DATA EXTRACTION AND SYNTHESIS: Random-effects models were fit using a bayesian network meta-analysis framework. Between-group comparisons were estimated using odds ratios (ORs) or mean differences with 95% credible intervals (CrIs). Treatment rankings were assessed by rank probabilities and the surface under the cumulative rank curve (SUCRA). MAIN OUTCOMES AND MEASURES: The primary outcome was EF (reintubation within 48 to 72 hours). Secondary outcomes were treatment failure (TF, reintubation plus NRS escalation or crossover to another NRS mode), pediatric intensive care unit (PICU) mortality, PICU and hospital length of stay, abdominal distension, and nasal injury. RESULTS: A total of 11 615 citations were screened, and 9 randomized clinical trials with a total of 1421 participants were included. Both CPAP and HFNC were found to be more effective than COT in reducing EF and TF (CPAP: OR for EF, 0.43; 95% CrI, 0.17-1.0 and OR for TF 0.27, 95% CrI 0.11-0.57 and HFNC: OR for EF, 0.64; 95% CrI, 0.24-1.0 and OR for TF, 0.34; 95% CrI, 0.16- 0.65). CPAP had the highest likelihood of being the best intervention for both EF (SUCRA, 0.83) and TF (SUCRA, 0.91). Although not statistically significant, BiPAP was likely to be better than COT for preventing both EF and TF. Compared to COT, CPAP and BiPAP were reported as showing a modest increase (approximately 3%) in nasal injury and abdominal distension. CONCLUSIONS AND RELEVANCE: The studies included in this systematic review and network meta-analysis found that compared with COT, EF and TF rates were lower with modest increases in abdominal distension and nasal injury. Of the modes evaluated, CPAP was associated with the lowest rates of EF and TF.

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