Less cholesterol means better tumor killing for cytotoxic T9 cells
| dc.contributor.author | Griesenauer, Brad | |
| dc.contributor.author | Paczesny, Sophie | |
| dc.contributor.department | Pediatrics, School of Medicine | en_US |
| dc.date.accessioned | 2019-05-23T19:20:40Z | |
| dc.date.available | 2019-05-23T19:20:40Z | |
| dc.date.issued | 2018-06-04 | |
| dc.description.abstract | In this issue, Ma et al. (https://doi.org/10.1084/jem.20171576) show that removal of cholesterol from CD8 T cells during type 9 differentiation increases their IL-9 production, persistence in vivo, and cytolytic function against tumors by preventing SUMOylation of liver X receptors. | en_US |
| dc.identifier.citation | Griesenauer, B., & Paczesny, S. (2018). Less cholesterol means better tumor killing for cytotoxic T9 cells. The Journal of experimental medicine, 215(6), 1505–1506. doi:10.1084/jem.20180852 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1805/19452 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Rockefeller University Press | en_US |
| dc.relation.isversionof | 10.1084/jem.20180852 | en_US |
| dc.relation.journal | The Journal of Experimental Medicine | en_US |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
| dc.source | PMC | en_US |
| dc.subject | Cholesterol | en_US |
| dc.subject | CD8 T cells | en_US |
| dc.subject | Type 9 differentiation | en_US |
| dc.subject | IL-9 production | en_US |
| dc.subject | Liver X receptors | en_US |
| dc.title | Less cholesterol means better tumor killing for cytotoxic T9 cells | en_US |
| dc.type | Article | en_US |