Hormonal suppression of mini-puberty in a neonate with mosaic 45X/46XY disorder of sexual development

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dc.contributor.authorKaefer, Martin
dc.contributor.authorEugster, Erica
dc.contributor.departmentMedicine, School of Medicineen_US
dc.date.accessioned2020-07-21T18:34:25Z
dc.date.available2020-07-21T18:34:25Z
dc.date.issued2020-05-03
dc.description.abstractDisorders of Sex Development (DSD) are some of the most controversial and challenging conditions that pediatric urologists treat. This may be especially true in mosaic 45X/46XY DSD, due to the inability to ascertain in the neonatal period which gender identity will best suit a given child with this condition. It has therefore been proposed to forgo any irreversible surgical interventions. In order to address the concern of early testosterone production in a nonsurgical manner we describe a case in which we treat a patient with a GnRH agonist to block the early physiologic rise in testosterone during the neonatal mini-puberty.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationKaefer, M., & Eugster, E. (2020). Hormonal suppression of mini-puberty in a neonate with mosaic 45X/46XY disorder of sexual development. Urology case reports, 32, 101237. https://doi.org/10.1016/j.eucr.2020.101237en_US
dc.identifier.urihttps://hdl.handle.net/1805/23306
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.eucr.2020.101237en_US
dc.relation.journalUrology Case Reportsen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourcePMCen_US
dc.subjectDisorder of sex developmenten_US
dc.subjectMini-pubertyen_US
dc.subjectGnRH agonisten_US
dc.subjectMosaicismen_US
dc.subjectTesticleen_US
dc.subjectTestosteroneen_US
dc.titleHormonal suppression of mini-puberty in a neonate with mosaic 45X/46XY disorder of sexual developmenten_US
dc.typeArticleen_US
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