Hormonal suppression of mini-puberty in a neonate with mosaic 45X/46XY disorder of sexual development
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2020-05-03
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American English
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Abstract
Disorders of Sex Development (DSD) are some of the most controversial and challenging conditions that pediatric urologists treat. This may be especially true in mosaic 45X/46XY DSD, due to the inability to ascertain in the neonatal period which gender identity will best suit a given child with this condition. It has therefore been proposed to forgo any irreversible surgical interventions. In order to address the concern of early testosterone production in a nonsurgical manner we describe a case in which we treat a patient with a GnRH agonist to block the early physiologic rise in testosterone during the neonatal mini-puberty.
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Kaefer, M., & Eugster, E. (2020). Hormonal suppression of mini-puberty in a neonate with mosaic 45X/46XY disorder of sexual development. Urology case reports, 32, 101237. https://doi.org/10.1016/j.eucr.2020.101237
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Urology Case Reports
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PMC
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