Deciphering genetic regulation at single-cell resolution in gastric cancer
| dc.contributor.author | Chen, Chengxuan | |
| dc.contributor.author | Han, Leng | |
| dc.contributor.department | Biostatistics and Health Data Science, Richard M. Fairbanks School of Public Health | |
| dc.date.accessioned | 2025-05-13T11:57:27Z | |
| dc.date.available | 2025-05-13T11:57:27Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Understanding cell-type-specific genetic regulation in gastric cancer is essential for uncovering disease susceptibility. By performing single-cell eQTL mapping in gastric tissues, Bian et al.1 identified previously uncharacterized regulatory genetic mechanisms, risk genes, and co-localization signals associated with gastric cancer susceptibility, providing insights into its pathogenesis and potential therapeutic approaches. | |
| dc.eprint.version | Final published version | |
| dc.identifier.citation | Chen C, Han L. Deciphering genetic regulation at single-cell resolution in gastric cancer. Cell Genom. 2025;5(4):100846. doi:10.1016/j.xgen.2025.100846 | |
| dc.identifier.uri | https://hdl.handle.net/1805/48030 | |
| dc.language.iso | en_US | |
| dc.publisher | Elsevier | |
| dc.relation.isversionof | 10.1016/j.xgen.2025.100846 | |
| dc.relation.journal | Cell Genomics | |
| dc.rights | Attribution-NonCommercial 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | |
| dc.source | PMC | |
| dc.subject | Genetic predisposition to disease | |
| dc.subject | Quantitative trait loci | |
| dc.subject | Single-cell analysis | |
| dc.subject | Stomach neoplasms | |
| dc.title | Deciphering genetic regulation at single-cell resolution in gastric cancer | |
| dc.type | Article |