Deciphering genetic regulation at single-cell resolution in gastric cancer
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2025
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American English
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Elsevier
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Abstract
Understanding cell-type-specific genetic regulation in gastric cancer is essential for uncovering disease susceptibility. By performing single-cell eQTL mapping in gastric tissues, Bian et al.1 identified previously uncharacterized regulatory genetic mechanisms, risk genes, and co-localization signals associated with gastric cancer susceptibility, providing insights into its pathogenesis and potential therapeutic approaches.
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Cite As
Chen C, Han L. Deciphering genetic regulation at single-cell resolution in gastric cancer. Cell Genom. 2025;5(4):100846. doi:10.1016/j.xgen.2025.100846
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Cell Genomics
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PMC
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Article
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Final published version