A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease

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dc.contributor.authorDuncan, Natalie A.
dc.contributor.authorKronenberger, William G.
dc.contributor.authorHampton, Kisha C.
dc.contributor.authorBloom, Ellen M.
dc.contributor.authorRampersad, Angeli G.
dc.contributor.authorRoberson, Christopher P.
dc.contributor.authorShapiro, Amy D.
dc.contributor.departmentDepartment of Psychiatry, IU School of Medicineen_US
dc.date.accessioned2017-04-05T16:51:41Z
dc.date.available2017-04-05T16:51:41Z
dc.date.issued2016
dc.description.abstractBACKGROUND: Antibiotic prophylaxis is a mainstay in sickle cell disease management. However, adherence is estimated at only 66%. This study aimed to develop and validate a Sickle Cell Antibiotic Adherence Level Evaluation (SCAALE) to promote systematic and detailed adherence evaluation. METHODS: A 28-item questionnaire was created, covering seven adherence areas. General Adherence Ratings from the parent and one health care provider and medication possession ratios were obtained as validation measures. RESULTS: Internal consistency was very good to excellent for the total SCAALE (α=0.89) and four of the seven subscales. Correlations between SCAALE scores and validation measures were strong for the total SCAALE and five of the seven subscales. CONCLUSION: The SCAALE provides a detailed, quantitative, multidimensional, and global measurement of adherence and can promote clinical care and research.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationDuncan, N. A., Kronenberger, W. G., Hampton, K. C., Bloom, E. M., Rampersad, A. G., Roberson, C. P., & Shapiro, A. D. (2016). A validated measure of adherence to antibiotic prophylaxis in children with sickle cell disease. Patient Preference and Adherence, 10, 983–992. http://doi.org/10.2147/PPA.S103874en_US
dc.identifier.urihttps://hdl.handle.net/1805/12184
dc.language.isoen_USen_US
dc.publisherDove Medical Pressen_US
dc.relation.isversionof10.2147/PPA.S103874en_US
dc.relation.journalPatient Preference and Adherenceen_US
dc.rightsAttribution-NonCommercial 3.0 United States
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/us
dc.sourcePMCen_US
dc.subjectSCAALEen_US
dc.subjectSickle SAFE Programen_US
dc.subjectcomplianceen_US
dc.subjecthemoglobinopathyen_US
dc.subjectnewborn screening programen_US
dc.subjectpenicillin prophylaxisen_US
dc.titleA validated measure of adherence to antibiotic prophylaxis in children with sickle cell diseaseen_US
dc.typeArticleen_US
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