Perivascular adipose tissue and coronary vascular disease

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dc.contributor.authorOwen, Meredith Kohr
dc.contributor.authorNoblet, Jillian N.
dc.contributor.authorSassoon, Daniel J.
dc.contributor.authorConteh, Abass M.
dc.contributor.authorGoodwill, Adam G.
dc.contributor.authorTune, Johnathan D.
dc.contributor.departmentDepartment of Cellular & Integrative Physiology, IU School of Medicineen_US
dc.date.accessioned2016-04-22T15:59:21Z
dc.date.available2016-04-22T15:59:21Z
dc.date.issued2014-08
dc.description.abstractCoronary perivascular adipose tissue is a naturally occurring adipose tissue depot that normally surrounds the major coronary arteries on the surface of the heart. Although originally thought to promote vascular health and integrity, there is a growing body of evidence to support that coronary perivascular adipose tissue displays a distinct phenotype relative to other adipose depots and is capable of producing local factors with the potential to augment coronary vascular tone, inflammation, and the initiation and progression of coronary artery disease. The purpose of the present review is to outline previous findings about the cardiovascular effects of coronary perivascular adipose tissue and the potential mechanisms by which adipose-derived factors may influence coronary vascular function and the progression of atherogenesis.en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationOwen, M. K., Noblet, J. N., Sassoon, D. J., Conteh, A. M., Goodwill, A. G., & Tune, J. D. (2014). Perivascular adipose tissue and coronary vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(8), 1643–1649. http://doi.org/10.1161/ATVBAHA.114.303033en_US
dc.identifier.issn1524-4636en_US
dc.identifier.urihttps://hdl.handle.net/1805/9384
dc.language.isoen_USen_US
dc.publisherOvid Technologies Wolters Kluwer -American Heart Associationen_US
dc.relation.isversionof10.1161/ATVBAHA.114.303033en_US
dc.relation.journalArteriosclerosis, Thrombosis, and Vascular Biologyen_US
dc.rightsPublisher Policyen_US
dc.sourcePMCen_US
dc.subjectAdipose Tissueen_US
dc.subjectmetabolismen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectCoronary Vesselsen_US
dc.titlePerivascular adipose tissue and coronary vascular diseaseen_US
dc.typeArticleen_US
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