Cancer Cachexia: Involvement of an Expanding Macroenvironment

dc.contributor.authorPryce, Benjamin R.
dc.contributor.authorWang, David J.
dc.contributor.authorZimmers, Teresa A.
dc.contributor.authorOstrowski, Michael C.
dc.contributor.authorGuttridge, Denis C.
dc.contributor.departmentSurgery, School of Medicine
dc.date.accessioned2024-09-18T09:12:32Z
dc.date.available2024-09-18T09:12:32Z
dc.date.issued2023
dc.description.abstractAdvanced cancers often present with the cachexia syndrome that impacts peripheral tissues, leading to involuntary weight loss and reduced prognosis. The central tissues undergoing depletion are skeletal muscle and adipose, but recent findings reveal an expanding tumor macroenvironment involving organ crosstalks that underlie the cachectic state.
dc.eprint.versionAuthor's manuscript
dc.identifier.citationPryce BR, Wang DJ, Zimmers TA, Ostrowski MC, Guttridge DC. Cancer cachexia: involvement of an expanding macroenvironment. Cancer Cell. 2023;41(3):581-584. doi:10.1016/j.ccell.2023.02.007
dc.identifier.urihttps://hdl.handle.net/1805/43383
dc.language.isoen_US
dc.publisherElsevier
dc.relation.isversionof10.1016/j.ccell.2023.02.007
dc.relation.journalCancer Cell
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectCachexia
dc.subjectSkeletal muscle
dc.subjectNeoplasms
dc.titleCancer Cachexia: Involvement of an Expanding Macroenvironment
dc.typeArticle
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