Cancer Cachexia: Involvement of an Expanding Macroenvironment
Date
2023
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American English
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Elsevier
Abstract
Advanced cancers often present with the cachexia syndrome that impacts peripheral tissues, leading to involuntary weight loss and reduced prognosis. The central tissues undergoing depletion are skeletal muscle and adipose, but recent findings reveal an expanding tumor macroenvironment involving organ crosstalks that underlie the cachectic state.
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Pryce BR, Wang DJ, Zimmers TA, Ostrowski MC, Guttridge DC. Cancer cachexia: involvement of an expanding macroenvironment. Cancer Cell. 2023;41(3):581-584. doi:10.1016/j.ccell.2023.02.007
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Cancer Cell
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PMC
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