Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss

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dc.contributor.authorClark, Andrew
dc.contributor.authorGhatak, Subhadip
dc.contributor.authorGuda, Poornachander Reddy
dc.contributor.authorEl Masry, Mohamed S.
dc.contributor.authorXuan, Yi
dc.contributor.authorSato, Amy Y.
dc.contributor.authorBellido, Teresita
dc.contributor.authorSen, Chandan K.
dc.contributor.departmentSurgery, School of Medicine
dc.date.accessioned2023-08-30T18:01:32Z
dc.date.available2023-08-30T18:01:32Z
dc.date.issued2022
dc.description.abstractThis work rests on our non-viral tissue nanotransfection (TNT) platform to deliver MyoD (TNT) to injured tissue in vivo. TNT was performed on skin and successfully induced expression of myogenic factors. TNT was then used as a therapy 7 days following volumetric muscle loss (VML) of rat tibialis anterior and rescued muscle function. TNT is promising as VML intervention.
dc.eprint.versionFinal published version
dc.identifier.citationClark, A., Ghatak, S., Guda, P. R., El Masry, M. S., Xuan, Y., Sato, A. Y., Bellido, T., & Sen, C. K. (2022). Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss. Npj Regenerative Medicine, 7(1), Article 1. https://doi.org/10.1038/s41536-022-00259-y
dc.identifier.other36266362
dc.identifier.urihttps://hdl.handle.net/1805/35259
dc.language.isoen
dc.publisherNature
dc.relation.isversionof10.1038/s41536-022-00259-y
dc.relation.journalNPJ Regenerative Medicine
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.sourcePublisher
dc.subjectnon-viral tissue nanotransfection
dc.subjectmuscle torque recovery
dc.subjectvolumetric muscle loss
dc.titleMyogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss
dc.typeArticle
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