False-negative Histoplasma antigen in acute pulmonary histoplasmosis: the value of urinary concentration by ultrafiltration and heat denaturation of serum proteins in detection of Histoplasma antigen
| dc.contributor.author | Srinivasan, Ashok | |
| dc.contributor.author | Kleiman, Martin B. | |
| dc.contributor.author | Debelenko, Larisa | |
| dc.contributor.author | Stokes, Dennis C. | |
| dc.contributor.author | De Vincenzo, John | |
| dc.contributor.author | Wheat, Joseph L. | |
| dc.contributor.department | Pediatrics, School of Medicine | en_US |
| dc.date.accessioned | 2018-05-09T20:38:16Z | |
| dc.date.available | 2018-05-09T20:38:16Z | |
| dc.date.issued | 2009-05 | |
| dc.description.abstract | We report an infant with localized pulmonary histoplasmosis in whom Histoplasma antibody assays, quantitative Histoplasma urine and serum antigen concentrations, and histopathologic findings of a mediastinal mass were nondiagnostic. A provisional diagnosis of histoplasmosis was established by using laboratory methods that increase the sensitivity of the antigen assay using ultrafiltration of urine and ethylenediaminetetraacetic acid/heat denaturation of serum proteins. | en_US |
| dc.eprint.version | Author's manuscript | en_US |
| dc.identifier.citation | Srinivasan, A., Kleiman, M. B., Debelenko, L., Stokes, D. C., De Vincenzo, J., & Wheat, J. L. (2009). False-negative Histoplasma antigen in acute pulmonary histoplasmosis: the value of urinary concentration by ultrafiltration and heat denaturation of serum proteins in detection of Histoplasma antigen. The Pediatric Infectious Disease Journal, 28(5), 447–449. https://doi.org/10.1097/INF.0b013e318193ecc1 | en_US |
| dc.identifier.issn | 0891-3668 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1805/16112 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Lippincott, Williams & Wilkins | en_US |
| dc.relation.isversionof | 10.1097/INF.0b013e318193ecc1 | en_US |
| dc.relation.journal | The Pediatric infectious disease journal | en_US |
| dc.rights | Publisher Policy | en_US |
| dc.source | PMC | en_US |
| dc.subject | histoplasmosis | en_US |
| dc.subject | urinary | en_US |
| dc.subject | serum | en_US |
| dc.subject | antigen | en_US |
| dc.title | False-negative Histoplasma antigen in acute pulmonary histoplasmosis: the value of urinary concentration by ultrafiltration and heat denaturation of serum proteins in detection of Histoplasma antigen | en_US |
| dc.type | Article | en_US |