Hydroxyurea reduces infections in children with sickle cell anemia in Uganda
| dc.contributor.author | Namazzi, Ruth | |
| dc.contributor.author | Bond, Caitlin | |
| dc.contributor.author | Conroy, Andrea L. | |
| dc.contributor.author | Datta, Dibyadyuti | |
| dc.contributor.author | Tagoola, Abner | |
| dc.contributor.author | Goings, Michael J. | |
| dc.contributor.author | Jang, Jeong Hoon | |
| dc.contributor.author | Ware, Russell E. | |
| dc.contributor.author | Opoka, Robert | |
| dc.contributor.author | John, Chandy C. | |
| dc.contributor.department | Pediatrics, School of Medicine | |
| dc.date.accessioned | 2024-07-15T16:12:18Z | |
| dc.date.available | 2024-07-15T16:12:18Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | After starting hydroxyurea treatment, Ugandan children with sickle cell anemia had 60% fewer severe or invasive infections, including malaria, bacteremia, respiratory tract infections, and gastroenteritis, than before starting hydroxyurea treatment (incidence rate ratio, 0.40 [ 95% confidence interval, 0.29-0.54 ]; P < .001 ). | |
| dc.eprint.version | Final published version | |
| dc.identifier.citation | Namazzi R, Bond C, Conroy AL, et al. Hydroxyurea reduces infections in children with sickle cell anemia in Uganda. Blood. 2024;143(14):1425-1428. doi:10.1182/blood.2023021575 | |
| dc.identifier.uri | https://hdl.handle.net/1805/42222 | |
| dc.language.iso | en_US | |
| dc.publisher | American Society of Hematology | |
| dc.relation.isversionof | 10.1182/blood.2023021575 | |
| dc.relation.journal | Blood | |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.source | PMC | |
| dc.subject | Sickle cell anemia | |
| dc.subject | Antisickling agents | |
| dc.subject | Hydroxyurea | |
| dc.subject | Malaria | |
| dc.title | Hydroxyurea reduces infections in children with sickle cell anemia in Uganda | |
| dc.type | Article |