Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

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Date
2024
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American English
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American Society of Hematology
Abstract

After starting hydroxyurea treatment, Ugandan children with sickle cell anemia had 60% fewer severe or invasive infections, including malaria, bacteremia, respiratory tract infections, and gastroenteritis, than before starting hydroxyurea treatment (incidence rate ratio, 0.40 [ 95% confidence interval, 0.29-0.54 ]; P < .001 ).

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Namazzi R, Bond C, Conroy AL, et al. Hydroxyurea reduces infections in children with sickle cell anemia in Uganda. Blood. 2024;143(14):1425-1428. doi:10.1182/blood.2023021575
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Blood
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PMC
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