Radioligands targeting purinergic P2X7 receptor

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dc.contributor.authorZheng, Qi-Huang
dc.contributor.departmentRadiology and Imaging Sciences, School of Medicineen_US
dc.date.accessioned2022-01-20T17:24:37Z
dc.date.available2022-01-20T17:24:37Z
dc.date.issued2020-06
dc.description.abstractThe purinergic P2X7 receptor (P2X7R) is an adenosine triphosphate (ATP) ligand-gated cationic channel receptor. P2X7R is closely associated with various inflammatory, immune, cancer, neurological, musculoskeletal and cardiovascular disorders. P2X7R is an interesting therapeutic target as well as molecular imaging target. This brief digest highlights the radioligands targeting P2X7R recently developed in drug discovery and molecular imaging agent development.en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationZheng, Q.-H. (2020). Radioligands targeting purinergic P2X7 receptor. Bioorganic & Medicinal Chemistry Letters, 30(12), 127169. https://doi.org/10.1016/j.bmcl.2020.127169en_US
dc.identifier.urihttps://hdl.handle.net/1805/27495
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.bmcl.2020.127169en_US
dc.relation.journalBioorganic & Medicinal Chemistry Lettersen_US
dc.rightsPublisher Policyen_US
dc.sourceAuthoren_US
dc.subjectPurinergic P2X7 receptoren_US
dc.subjectradioligandsen_US
dc.subjectdrug discoveryen_US
dc.titleRadioligands targeting purinergic P2X7 receptoren_US
dc.typeArticleen_US
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