Radioligands targeting purinergic P2X7 receptor
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2020-06
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English
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Elsevier
Abstract
The purinergic P2X7 receptor (P2X7R) is an adenosine triphosphate (ATP) ligand-gated cationic channel receptor. P2X7R is closely associated with various inflammatory, immune, cancer, neurological, musculoskeletal and cardiovascular disorders. P2X7R is an interesting therapeutic target as well as molecular imaging target. This brief digest highlights the radioligands targeting P2X7R recently developed in drug discovery and molecular imaging agent development.
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Zheng, Q.-H. (2020). Radioligands targeting purinergic P2X7 receptor. Bioorganic & Medicinal Chemistry Letters, 30(12), 127169. https://doi.org/10.1016/j.bmcl.2020.127169
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Bioorganic & Medicinal Chemistry Letters
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