Skeletal accumulation of fluorescently-tagged zoledronate is higher in animals with early stage chronic kidney disease

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dc.contributor.authorSwallow, Elizabeth A.
dc.contributor.authorAref, Mohammad W.
dc.contributor.authorChen, Neal
dc.contributor.authorByiringo, Innocent
dc.contributor.authorHammond, Max A.
dc.contributor.authorMcCarthy, Brian P.
dc.contributor.authorTerrito, Paul R.
dc.contributor.authorKamocka, Malgorzata M.
dc.contributor.authorWinfree, Seth
dc.contributor.authorDunn, Kenneth W.
dc.contributor.authorMoe, Sharon M.
dc.contributor.authorAllen, Matthew R.
dc.contributor.departmentAnatomy and Cell Biology, School of Medicineen_US
dc.date.accessioned2019-08-02T14:16:40Z
dc.date.available2019-08-02T14:16:40Z
dc.date.issued2018-09-01
dc.description.abstractThis work examines the skeletal accumulation of fluorescently-tagged zoledronate in an animal model of chronic kidney disease. The results show higher accumulation 24-hours post-dose in animals with lower kidney function due to greater amounts of binding at individual surfaces.en_US
dc.description.sponsorshipNIH F30 DK115162; NIH T32 AR065971; NIH P30 DK 079312en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationSwallow EA, Aref MW, Chen N, Byiringiro I, Hammond MA, McCarthy BP, Territo PR, Kamocka MM, Winfree S, Dunn KW, Moe SM. Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease. Osteoporosis International. 2018 Sep 1;29(9):2139-46.en_US
dc.identifier.urihttps://hdl.handle.net/1805/20148
dc.publisherSpringeren_US
dc.relation.isversionof10.1007/s00198-018-4589-3en_US
dc.relation.journalOsteoporosis Internationalen_US
dc.sourceAuthoren_US
dc.subjectBone Density Conservation Agentsen_US
dc.subjectBone and Bonesen_US
dc.subjectChronic Renal Insufficiencyen_US
dc.subjectZoledronic Aciden_US
dc.titleSkeletal accumulation of fluorescently-tagged zoledronate is higher in animals with early stage chronic kidney diseaseen_US
dc.typeArticleen_US
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