Skeletal accumulation of fluorescently-tagged zoledronate is higher in animals with early stage chronic kidney disease
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2018-09-01
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Springer
Abstract
This work examines the skeletal accumulation of fluorescently-tagged zoledronate in an animal model of chronic kidney disease. The results show higher accumulation 24-hours post-dose in animals with lower kidney function due to greater amounts of binding at individual surfaces.
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Cite As
Swallow EA, Aref MW, Chen N, Byiringiro I, Hammond MA, McCarthy BP, Territo PR, Kamocka MM, Winfree S, Dunn KW, Moe SM. Skeletal accumulation of fluorescently tagged zoledronate is higher in animals with early stage chronic kidney disease. Osteoporosis International. 2018 Sep 1;29(9):2139-46.
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NIH F30 DK115162;
NIH T32 AR065971;
NIH P30 DK 079312
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Osteoporosis International
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Article
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Author's manuscript