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2024 IUSM Education Day
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Item Social Determinants of Health Associated with Inpatient Admissions for Congestive Heart Failure, Diabetes, Chronic Obstructive Pulmonary Disease, and Asthma(2023-07) Deckbar, John Quentin; DeMichael, Kelly; Gad, Wael; Guerrero, Jonathan; Muvuka, BarakaIntroduction: The CDC and American Lung Association estimate that congestive heart failure (CHF), diabetes, chronic obstructive pulmonary disorder (COPD), and asthma (COPD/asthma) cost Americans $30.7 billion, $327 billion, and $50 billion respectively each year. They account for most inpatient readmissions at St. Mary Medical Center (SMMC), an urban hospital in Northwest Indiana. There is need for further research on the social, behavioral, and demographic determinants associated with these conditions. This study examined the social, behavioral, and demographic determinants associated with inpatient admission for CHF, diabetes, COPD/asthma in SMMC’s service area. Methods: This retrospective study was part of a multi-phased Community-Based Participatory Research partnership between SMMC and Indiana University School of Medicine Northwest. SMMC implemented a pilot screening and referral program to assess social determinants of health in their service area as part of their Hospital Readmission Reduction Program. This study included data from 10,953 inpatient admissions between January 2021 to March 2023, majority of whom were transferred from the emergency department. Data analysis consisted of univariate, bivariate (Chi-square), and multivariate (binary logistic regression) analysis in SPSS 29.0. Results: Bivariate analysis revealed a statistically significant association between CHF and smoking, age, insurance type, and income. Diabetes was significantly associated with smoking, smokeless tobacco use, age group, race, income, and sex. COPD/asthma was significantly associated with smoking, age group, transportation needs, stress, insurance, ethnicity, and sex. Multivariate analysis found the following significant associations: age group with both CHF (p<0.001) and diabetes (p<0.001), former smoking with both CHF (p = 0.007) and COPD/asthma (p = 0.049), current smoking with COPD/asthma (p = 0.016), and sex with diabetes (p <0.001). Conclusions: These findings indicate significant associations between multiple socio-behavioral factors and admission for CHF, diabetes, COPD/asthma. Multi-risk-factor interventions may address these interactions and contribute to reducing readmission.Item Exploring a Transcriptome-forward Approach for Genetic Evaluation in Thoracic Aortopathy(2023-07-28) Stanley, Katherine; Landis, BenjaminBackground/Objective: Thoracic aortic aneurysm (TAA) is an aortopathy that predisposes to aortic dissection and rupture. Transcriptomic analysis has diagnostic utility in other diseases, but this has not been developed for TAA. We therefore sought to implement the Genome Analysis Toolkit (GATK) as a tool for high-throughput detection of novel variants in RNA sequencing (RNA-seq) data from patients with TAA. Methods: Human proximal aortic tissue samples from 63 TAA patients and 15 controls were used to establish primary smooth muscle cell (SMC) lines in culture. Total RNA was extracted at early passage; RNA-seq was performed using 150 base pair paired-end reads. Variants were called from RNA-seq reads using the GATK’s HaplotypeCaller tool. The MarkDuplicates tool tagged duplicate reads, but these were retained for variant analysis. Singletons were defined as heterozygous variants unique to one sample in the overall group. Results: The RNA-seq pipeline was validated by confirming known mutations in 2 patients, inspecting reads directly in the Integrative Genomics Viewer (IGV), and genotyping for a common single nucleotide polymorphism. Across all 78 samples, the GATK pipeline identified 4,823,462 variant sites, 236,495 of which were in coding regions. Variant sites were filtered for those located within the coding regions of 31 genes curated for known evidence of aortic disease causality. Among the 511 coding variant sites in these genes, 330 single nucleotide variants and 33 insertions/deletions were identified as singletons. Singleton variant calls were evaluated for quality and annotated in order to predict their likelihood of pathogenicity, thus far identifying strong candidate causal variants in FBN1, TGFBR1, TGFB3, GATA4, and HEY2. Conclusion: Application of the GATK RNA-seq pipeline expands our prior IGV analysis, further demonstrating the potential diagnostic utility of transcriptomic analysis of aortic SMCs in TAA. Scientific Impact: Identifying novel aortopathy-associated variants could improve future disease detection and prediction of severity. Presentation recording available online: https://purl.dlib.indiana.edu/iudl/media/059c18mr8hItem Statewide Synergy: Showcasing Scholarship and Innovation in Medical Education at IUSM, 2020-2024(2024) Kochhar, Komal; Soleimani, Leila; Byrne, Bobbi; Stefanidis, Dimitrios; Pettit, Katie; Zakeri, Bita; Denny, Kim; McNulty , Margaret; Hoffman, Leslie; Brokaw, James; Wallach, PaulBackground IUSM employs a large geographically distributed system of medical education composed of 8 regional medical campuses statewide with the main medical campus in Indianapolis. An inherent challenge of operating such a large multi-campus system is being able to provide relevant professional development opportunities for all our medical educators and staff from across the state, as well as to provide our learners with formative opportunities to engage with faculty and peers in a community of scholars. Study objective We planned and implemented a one-day event available to all faculty, staff, and learners from across our multi-campus system with a focus on medical education scholarship. Methods In March 2020, the first Education Day took place on the Indianapolis campus, orchestrated by a five-member Planning Committee from the Dean’s Office of Educational Affairs. Peer-reviewed proposals culminated in oral and poster presentations, workshops, and group discussions. Eight themed sessions included presentations about specific aspects of IUSM’s educational mission: Diversity, Equity & Inclusion, Wellness, Point-of-Care Ultrasound, Simulation, Undergraduate Medical Education, Graduate Medical Education, Regional Medical Campuses, and Biomedical (MS/PhD) Education. A lunchtime keynote address was given by a nationally recognized medical educator. The day-long event ended with an awards ceremony to recognize the “best” faculty, staff, and learner proposals. With minimal variation, a similar planning process and agenda were used for the subsequent Education Days held in late April 2021 (virtual), 2022, and 2023. About 40 faculty reviewers from across campuses reviewed submissions using a standard rubric. Each submission was reviewed by two reviewers with a third reviewer resolving any split decisions. Accepted proposals were archived in the University’s ScholarWorks Digital Repository to extend their reach. Results Over four years, an average of 132 proposals were reviewed annually, with attendance averaging 281, trending upwards each year. While most attendees were from Indianapolis campus (76%), participation from the RMCs (24%) increased each year. Attendees represented basic science departments (17%), clinical departments (61%), and other school units, e.g., library, Dean’s offices, etc. (22%). Education Day presenters included faculty (38%), staff (12%), and learners (50%). The “learners” included medical students, residents, fellows, and a few graduate students. Beginning in 2022, we included Scholarly Concentration projects from medical students statewide which were presented during a special poster session. Post-event survey data across the four years revealed high satisfaction, with 81% rating the event as “excellent” or “very good.” Majority “strongly agreed” or “agreed” that Education Day met their professional expectations and needs (88%); provided supporting material/tools helpful to their professional role (83%); and included opportunities to learn interactively (82%). As a result of this event, majority “strongly agreed” or “agreed” they will be better able to network and collaborate with other IUSM colleagues (87%), identify best practices in medical education (81%), learn to present and publish educational outcomes data (75%), and describe current approaches to evaluate learners (73%). Conclusions IUSM’s Annual Education Day has established itself as a successful venue to share educational best practices, forge new collaborations, and encourage participation from all IUSM campuses.Item Faculty Learning Communities: A Collaborative Model for Professional Development of Medical Educators in our Multi-Campus System, 2019 to Present(2024) Kochhar, Komal; Longtin, Krista; WIlson, Shawn; Ho, Monling; Hobson, Tara; Holley, Matthew; Brokaw, James; Wallach, PaulBackground The Indiana University School of Medicine employs a large geographically distributed system of medical education composed of 8 regional medical campuses and the main medical campus in Indianapolis. Medical educators need targeted faculty development programs to give them the skills necessary to produce educational scholarship for promotion and tenure. An inherent challenge of operating such a large multi-campus system is being able to provide relevant professional development opportunities for all our medical educators across the state. Objective To provide relevant professional development opportunities for all medical education faculty across our large multi-campus system statewide. Methods Beginning the Fall of 2019, we implemented Faculty Learning Communities (FLCs) specifically designed to develop faculty competence in medical education research. All medical school faculty across our statewide system were eligible to participate. Each FLC team consisted of 4-6 medical educators engaged in a collaborative educational research project led by an experienced faculty mentor. The FLC teams met monthly via Zoom over a 2-year term to establish priorities, share ideas, distribute the workload, and produce the scholarly product(s). In addition to the group work, participants were expected to attend a series of monthly webinars to build foundational skills in educational research. Results To date, 63 medical educators (both preclinical/clinical) have participated in 13 FLC teams. To assess participant satisfaction, surveys were administered at the mid-point and at the end of each FLC team’s term (68% cumulative response rate). Averaged across all teams, a majority of respondents: Rated their FLC experience as “Good” to “Excellent” (81%) “Strongly agreed” or “agreed” that the FLC process met their professional development needs (73%) Were interested in participating in future FLC teams (65%) By the end of their term, about one-half of the participants had submitted their work for publication or presentation. Conclusion By participating in FLCs, medical educators from the regional campuses and main campus were able to effectively collaborate on projects of mutual interest. In our experience, FLCs provide a cost-effective and sustainable model for developing medical educators. Although lack of protected time may be an impediment for clinician participation, this can be partially mitigated by requiring the clinical chair’s approval before joining an FLC team.Item Perceptions and Barriers to Care for Burmese Refugees, a multi-method qualitative study(2024-04-25) Nadeem, Manahil; Messmore, NikiBACKGROUND Since 2015, Indiana has been home to over 40,000 Burmese refugees (1). Although the Model Minority Myth would lead U.S. policymakers to believe that all Asian Americans are wealthy, overwhelmingly have college degrees, and have access to health insurance, this is a fallacy (2). According to the Pew Research Center, only 38% of Burmese residents in the U.S. speak English and 25% of Burmese residents experience poverty. Although there is little research on Burmese health outcomes in the U.S., research points to poor health outcomes (3). STUDY OBJECTIVE/HYPOTHESIS This research project aims to identify the barriers and perceptions to healthcare for Burmese refugees and provide plausible solutions. This project includes a narrative review of the existing literature combined with interviews with physicians who specialize in immigrant care. METHODS A narrative review was conducted via PubMed and Google Scholar to analyze the research published on the healthcare of Burmese refugees in the United States. Search terms and MESH terms like refugees, Myanmar, Burma, southeast Asian people, Rohingya, health services accessibility, health status disparities, social determinants of health, and socioeconomic factors were used. Ultimately, 40 articles were included. Interviews with physicians specializing in immigrant care in Indianapolis were also conducted and included in this study. The project includes interviews from Dr. Ashley Overley, CEO of Sandra Eskenazi Mental Health Center, and Dr. Maurice Henein, a family medicine physician at Community Health Network's Center for International Health. RESULTS 40 articles, published in 2005-2023, were included and analyzed for themes. The barriers to care for Burmese refugees are related to languages & communication, healthcare structure, pediatric care, reproductive care, and mental health. Many articles expressed a dire need for reliable interpreters and trauma-informed care (4,5). Moreover, cost and the concept of preventative care are the largest barriers relating to healthcare structure. For pediatric care, research indicates that Burmese parents feel that physicians do not obtain proper consent before treating their children. (6,7,8). Mental health is often equated to craziness when translated and is difficult to navigate with patients (11). Lastly, research found that Burmese women wanted to talk about sex during their health visits, but did not want to initiate the conversation themselves (14,15). Interviews with expert physicians were included in this study. The interviewers expressed that physicians should mobilize community partners and take part in cultural trainings. CONCLUSION AND RECOMMENDATIONS This project aimed to evaluate healthcare for Burmese refugees and provide solutions accordingly. After analyzing the research, it is critical we advocate for reliable interpreters for our patients. Without proper communication, it is impossible to build rapport and trust. Moreover, physicians should educate their patients about the importance of preventative care, mental health, and reproductive health screenings. To improve the quality of care they provide, physicians should initiate workshops and empower community organizations that are providing help to their patients. Indianapolis is home to one of the largest populations of Burmese refugees; it is time we provide the best healthcare for them.Item Tips to Leverage Your ORCID(2024-04-26) Dolan, Levi; Craven, Hannah J.; Ramirez, Mirian; Whipple, Elizabeth C.Introduction/Background: An effective scholarly presence means not only publishing research, but also connecting research outputs to an online professional identity. ORCID (Open Research and Contributor ID) is a not-for-profit organization that allows researchers to create a unique persistent identifier to organize their bibliography, datasets, grants, and other works. An ORCID is affiliation-agnostic and keeps researchers with similar names distinct, increasing attribution accuracy. Workshop Objectives: By connecting their ORCID profile to existing systems, researchers can benefit from automated updates that support validation and efficient presentation of their scholarly outputs. After introducing how to create an ORCID profile, this workshop will move beyond ORCID basics and walk through how to maximize the benefits of a centralized online presence for a researcher’s works. Methods: This workshop will focus on the steps for setting up connections with three major systems for populating ORCID profiles: CrossRef (an aggregator of metadata for scholarly literature publication outlets), DataCite (similar to CrossRef, but focused on data repositories), and Scopus (one of the most powerful scholarly publishing databases for managing author affiliation information). Attendees will participate in the hands-on processes needed to set up their ORCID profiles if needed, and to open these connections so that in the future they will not need to manually enter data for their profiles to be updated, minimizing maintenance time needed to maintain their scholarly presence. Learning Goals: Attendees can expect to leave this workshop with a robust persistent record of their research outputs. This will increase the findability and reusability of their research, which will provide avenues for greater scholarly impact. An ORCID profile is not a prerequisite for attending.Item Advancing AI in Medical Education: Understanding the Malpractice Landscape(2024-04-26) Stephanian, Brooke; Karki, Sabin; Schantz, EliItem Characteristics associated with access to kidney transplantation services in the Ohio River Valley(2024-04-26) Kelty, Catherine; Buford, Jade; Drewry, Kelsey; Adebiyi, Oluwafisayo; Sharfuddin, Asif; Fridell, Jonathan; Sher, Jawad; Huml, Anne; Moe, Sharon; Patzer, RachelItem “I’m supposed to be a helper”: Spiritual distress of abortion providers after Dobbs v. Jackson(2024-04-26) Bode, Leah; Kumar, Komal; McQuillan, Josie; Scott, Nicole; Bernard, CaitlinINTRO On June 24, 2022, the U.S. Supreme Court voted to overturn Roe v. Wade, the 1970 landmark case protecting abortion rights in America, in Dobbs v. Jackson Women’s Health Organization. The decision has the potential to affect the way that abortion providers practice their specialty by interacting with patients and making meaning from their work. Meaning making in one’s work has been shown to be integral in fostering spiritual well-being and preventing burnout in medicine. We sought to demonstrate the spectrum of spirituality of abortion providers and their subsequent spiritual distress in the aftermath of Dobbs. METHODS We conducted thirty-minute interviews on Zoom with 26 abortion providers from 17 states from November 2022 to February 2023. Demographics collected included age, racial identity, location of practice (by state), years in practice, fellowship training, and practice setting (community, academic, hybrid). States were then classified according to the Guttmacher Institute classifications of Most restrictive, Restrictive, Some restrictions/protections, Protective, and Very protective as of December 2022. Interviews consisted of questions such as "What are the major tenants of your spiritual beliefs (if none, how you make meaning)?” and “Tell me about any spiritual distress or alienation from your religious or spiritual community as a result of the Dobbs decision.” Interviews were analyzed using NVivo 14. RESULTS Providers were equally distributed amongst community (34.6%), academic (34.6%), and hybrid (30.8%) settings. Location of practice (state) was well-distributed across the restrictive-protective spectrum: 7.7% Most restrictive, 30.8% Restrictive, 15.4% Some restrictions/protections, 30.8% Protective, and 15.4% Very protective. The majority of participants identified a personal spirituality, while less than half were tied to an organized religion. Sixteen participants (61.5%) cited ethical principles of justice, non-maleficence, respect for human life, or autonomy as major tenets of their spirituality. Ten subjects (38.5%) felt spiritually called to provide abortion care, 11 others (42.3%) perceived abortion care as a spiritual obligation, and 12 participants (46.2%) noted the act of providing an abortion as a spiritual act, for provider and/or patient. Most participants experienced spiritual distress relating to the Dobbs decision. Those who did not experience spiritual distress (26%) noted location and the alignment of their work with spiritual values as protective factors. Of note, 92% of participants described their spirituality as helpful in coping with the fall of Roe v. Wade. Sources of strength included advocacy, agency (e.g., “I feel strength knowing that I’m still able to do this job”), legislative work, and community; 57.7% specifically cited the abortion provider community. CONCLUSION The decision to be an abortion provider is often motivated by one’s spiritual identity. Many abortion providers endorsed feelings of spiritual distress related to not being able to comply with their moral and/or spiritual obligation of providing abortions secondary to new restrictions. Location factored heavily into whether providers were experiencing this distress, suggesting that state restrictions on abortions have directly impacted the spiritual well-being of abortion providers. As many laws pertaining to abortion are influenced by religious beliefs, it is important to recognize that abortion providers themselves are overwhelming spiritual.Item Ethical Boundaries in AI-Driven Medical Education: Safeguarding Patient Data(2024-04-26) Karki, Sabin; Stephanian, Brooke; Schantz, Eli