Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment

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dc.contributor.authorGoukasian, Naira
dc.contributor.authorPorat, Shai
dc.contributor.authorBlanken, Anna
dc.contributor.authorAvila, David
dc.contributor.authorZlatev, Dimitar
dc.contributor.authorHurtz, Sona
dc.contributor.authorHwang, Kristy S.
dc.contributor.authorPierce, Jonathan
dc.contributor.authorJoshi, Shantanu H.
dc.contributor.authorWoo, Ellen
dc.contributor.authorApostolova, Liana G.
dc.contributor.departmentNeurology, School of Medicineen_US
dc.date.accessioned2019-12-27T18:58:08Z
dc.date.available2019-12-27T18:58:08Z
dc.date.issued2019-08-13
dc.description.abstractWe analyzed structural magnetic resonance imaging data from 58 cognitively normal and 101 mild cognitive impairment subjects. We used a general linear regression model to study the association between cognitive performance with hippocampal atrophy and ventricular enlargement using the radial distance method. Bilateral hippocampal atrophy was associated with baseline and longitudinal memory performance. Left hippocampal atrophy predicted longitudinal decline in visuospatial function. The multidomain ventricular analysis did not reveal any significant predictors.en_US
dc.identifier.citationGoukasian, N., Porat, S., Blanken, A., Avila, D., Zlatev, D., Hurtz, S., … Apostolova, L. G. (2019). Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment. Dementia and geriatric cognitive disorders extra, 9(2), 281–293. doi:10.1159/000490044en_US
dc.identifier.urihttps://hdl.handle.net/1805/21608
dc.language.isoen_USen_US
dc.publisherKargeren_US
dc.relation.isversionof10.1159/000490044en_US
dc.relation.journalDementia and Geriatric Cognitive Disorders Extraen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourcePMCen_US
dc.subjectAlzheimer's diseaseen_US
dc.subjectMild cognitive impairmenten_US
dc.subjectImagingen_US
dc.subjectMRIen_US
dc.subjectHippocampal atrophyen_US
dc.subjectVentricular enlargementen_US
dc.titleCognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairmenten_US
dc.typeArticleen_US
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