Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2)

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dc.contributor.authorLange, Lara M.
dc.contributor.authorAvenali, Micol
dc.contributor.authorEllis, Melina
dc.contributor.authorIllarionova, Anastasia
dc.contributor.authorKeller Sarmiento, Ignacio J.
dc.contributor.authorTan, Ai-Huey
dc.contributor.authorMadoev, Harutyun
dc.contributor.authorGalandra, Caterina
dc.contributor.authorJunker, Johanna
dc.contributor.authorRoopnarain, Karisha
dc.contributor.authorSolle, Justin
dc.contributor.authorWegel, Claire
dc.contributor.authorFang, Zih-Hua
dc.contributor.authorHeutink, Peter
dc.contributor.authorKumar, Kishore R.
dc.contributor.authorLim, Shen-Yang
dc.contributor.authorValente, Enza Maria
dc.contributor.authorNalls, Mike
dc.contributor.authorBlauwendraat, Cornelis
dc.contributor.authorSingleton, Andrew
dc.contributor.authorMencacci, Niccolo
dc.contributor.authorLohmann, Katja
dc.contributor.authorKlein, Christine
dc.contributor.authorGlobal Parkinson’s Genetic Program (GP2)
dc.contributor.departmentMedical and Molecular Genetics, School of Medicine
dc.date.accessioned2024-01-25T17:00:26Z
dc.date.available2024-01-25T17:00:26Z
dc.date.issued2023-06-27
dc.description.abstractThe Monogenic Network of the Global Parkinson’s Genetics Program (GP2) aims to create an efficient infrastructure to accelerate the identification of novel genetic causes of Parkinson’s disease (PD) and to improve our understanding of already identified genetic causes, such as reduced penetrance and variable clinical expressivity of known disease-causing variants. We aim to perform short- and long-read whole-genome sequencing for up to 10,000 patients with parkinsonism. Important features of this project are global involvement and focusing on historically underrepresented populations.
dc.eprint.versionFinal published version
dc.identifier.citationLange LM, Avenali M, Ellis M, et al. Elucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2) [published correction appears in NPJ Parkinsons Dis. 2023 Sep 13;9(1):133]. NPJ Parkinsons Dis. 2023;9(1):100. Published 2023 Jun 27. doi:10.1038/s41531-023-00526-9
dc.identifier.urihttps://hdl.handle.net/1805/38197
dc.language.isoen_US
dc.publisherSpringer Nature
dc.relation.isversionof10.1038/s41531-023-00526-9
dc.relation.journalNPJ Parkinsons Disease
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.sourcePMC
dc.subjectSequencing
dc.subjectParkinson's disease
dc.titleElucidating causative gene variants in hereditary Parkinson's disease in the Global Parkinson's Genetics Program (GP2)
dc.typeArticle
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