A Case of Autoimmune Hemolytic Anemia after the First Dose of COVID-19 mRNA-1273 Vaccine with Undetected Pernicious Anemia
dc.contributor.author | Jaydev, Fnu | |
dc.contributor.author | Kumar, Vinod | |
dc.contributor.author | Khatri, Jaikumar | |
dc.contributor.author | Shahani, Shobha | |
dc.contributor.author | Beganovic, Sead | |
dc.contributor.department | Medicine, School of Medicine | en_US |
dc.date.accessioned | 2023-04-28T10:34:49Z | |
dc.date.available | 2023-04-28T10:34:49Z | |
dc.date.issued | 2022-01-29 | |
dc.description.abstract | By this time, multiple vaccines have been approved to limit the spread of SARS-CoV-2 worldwide. These include new-generation vaccines that contain mRNA of the target organism. Some common side effects were identified and reported during phase 3 clinical trials of vaccination, but more rare adverse events were reported in the literature. One such concern is autoimmune conditions that SARS-CoV-2 viral antigens could have possibly incited. We are presenting here a case of a young female with no known autoimmune diseases, diagnosed with autoimmune hemolytic anemia about a week after receiving her first dose of the COVID-19 mRNA vaccine. We discuss the possible culprit for precipitation of autoimmune hemolytic anemia after the SARS-CoV-2 mRNA vaccine, which encodes virus spike protein. This case highlights the importance of being vigilant for identifying rare adverse events that could appear during mass vaccination. | en_US |
dc.eprint.version | Final published version | en_US |
dc.identifier.citation | Jaydev F, Kumar V, Khatri J, Shahani S, Beganovic S. A Case of Autoimmune Hemolytic Anemia after the First Dose of COVID-19 mRNA-1273 Vaccine with Undetected Pernicious Anemia. Case Rep Hematol. 2022;2022:2036460. Published 2022 Jan 29. doi:10.1155/2022/2036460 | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/32682 | |
dc.language.iso | en_US | en_US |
dc.publisher | Hindawi | en_US |
dc.relation.isversionof | 10.1155/2022/2036460 | en_US |
dc.relation.journal | Case Reports in Hematology | en_US |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.source | PMC | en_US |
dc.subject | Vaccines | en_US |
dc.subject | SARS-CoV-2 | en_US |
dc.subject | mRNA | en_US |
dc.subject | Side effects | en_US |
dc.subject | Autoimmune conditions | en_US |
dc.subject | Viral antigens | en_US |
dc.title | A Case of Autoimmune Hemolytic Anemia after the First Dose of COVID-19 mRNA-1273 Vaccine with Undetected Pernicious Anemia | en_US |
dc.type | Article | en_US |