Histoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxis

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dc.contributor.authorAgrawal, Vaibhav
dc.contributor.authorBrinda, Bryan J.
dc.contributor.authorFarag, Sherif S.
dc.contributor.departmentMedicine, School of Medicineen_US
dc.date.accessioned2020-04-09T12:09:29Z
dc.date.available2020-04-09T12:09:29Z
dc.date.issued2020-02-12
dc.description.abstractHistoplasma capsulatum infection is a rare complication in the allogeneic stem cell transplant patients. Minimal guidance exists on how to appropriately manage histoplasmosis in these patients. We report a patient who developed Histoplasma pneumonia while receiving voriconazole prophylaxis at a therapeutic trough level. The patient experienced significant clinical improvement after initiation of itraconazole pharmacotherapy. We recommend a lower threshold for evaluation for histoplasmosis in allogeneic hematopoietic stem cell transplant recipients who live in endemic regions, regardless of their antifungal prophylactic regimen.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationAgrawal, V., Brinda, B. J., & Farag, S. S. (2020). Histoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxis. Case reports in hematology, 2020, 8124137. https://doi.org/10.1155/2020/8124137en_US
dc.identifier.urihttps://hdl.handle.net/1805/22516
dc.language.isoen_USen_US
dc.publisherHindawien_US
dc.relation.isversionof10.1155/2020/8124137en_US
dc.relation.journalCase Reports in Hematologyen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0*
dc.sourcePMCen_US
dc.subjectHistoplasma capsulatumen_US
dc.subjectItraconazole pharmacotherapyen_US
dc.subjectAllogeneic hematopoietic stem cell transplantsen_US
dc.subjectEndemic regionsen_US
dc.subjectImmunocompromised patientsen_US
dc.titleHistoplasma capsulatum Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient Receiving Voriconazole Prophylaxisen_US
dc.typeArticleen_US
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