A Comparative Analysis of Negative Pressure Wound Therapy Methods for Sternal Wound Infections

dc.contributor.authorBamba, Ravinder
dc.contributor.authorHarvey, Brianna I.
dc.contributor.authorMalik, Noor U.
dc.contributor.authorHiggins, Jasmine
dc.contributor.authorSung, Cynthia
dc.contributor.authorCorvera, Joel S.
dc.contributor.authorHartman, Brett C.
dc.contributor.authorHassanein, Aladdin H.
dc.contributor.authorLester, Mary E.
dc.contributor.departmentSurgery, School of Medicine
dc.date.accessioned2025-04-17T12:32:02Z
dc.date.available2025-04-17T12:32:02Z
dc.date.issued2025-03-07
dc.description.abstractSternal wound infection can be a severe complication of cardiac surgery. Multiple debridements are often necessary before definitive coverage, and negative pressure wound therapy (NPWT) is often used as a temporary dressing between debridements. NPWT with instillation and dwell (NPWT-i) has been used in many wound types including sternal wounds with success. The purpose of this study was to compare outcomes between sternal wounds managed with conventional NPWT and NPWT-i. A total of 47 patients who had sternal wound infections were managed with debridement, negative pressure therapy, and flap. Patients were divided into 2 groups based on the type of negative pressure therapy: NPWT (n = 24) and NPWT-i (n = 23). The NPWT group required 3.3 debridements per patient before flap coverage, whereas the NPWT-i group required 3.4 debridements per patient (P = 0.86). Other postoperative outcomes including seroma, hematoma, delayed wound healing, and surgical site infection were similar between the 2 groups. We found NPWT similar to NPWT-i for the number of debridements needed and outcomes in the management of sternal wound infections. NPWT-i does not replace or decrease the need for operative debridement in sternal wounds.
dc.eprint.versionFinal published version
dc.identifier.citationBamba R, Harvey BI, Malik NU, et al. A Comparative Analysis of Negative Pressure Wound Therapy Methods for Sternal Wound Infections. Plast Reconstr Surg Glob Open. 2025;13(3):e6579. Published 2025 Mar 7. doi:10.1097/GOX.0000000000006579
dc.identifier.urihttps://hdl.handle.net/1805/47107
dc.language.isoen_US
dc.publisherWolters Kluwer
dc.relation.isversionof10.1097/GOX.0000000000006579
dc.relation.journalPlastic and Reconstructive Surgery Global Open
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourcePMC
dc.subjectSternal wound infection
dc.subjectCardiac surgery
dc.subjectDebridements
dc.subjectNegative pressure wound therapy (NPWT)
dc.titleA Comparative Analysis of Negative Pressure Wound Therapy Methods for Sternal Wound Infections
dc.typeArticle
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