Minimal Clinically Important Difference for the Rasch Neuropsychiatric Inventory Irritability and Aggression Scale for Traumatic Brain Injury

dc.contributor.authorMalec, James F.
dc.contributor.authorHammond, Flora M.
dc.contributor.departmentPhysical Medicine and Rehabilitation, School of Medicineen_US
dc.date.accessioned2017-11-10T18:16:28Z
dc.date.available2017-11-10T18:16:28Z
dc.date.issued2017
dc.description.abstractObjective To determine the minimal clinically important difference (MCID) for a Rasch measure derived from the Irritability/Lability and Agitation/Aggression subscales of the Neuropsychiatric Inventory (NPI)—the Rasch NPI Irritability and Aggression Scale for Traumatic Brain Injury (NPI-TBI-IA). Design Distribution-based statistical methods were applied to retrospective data to determine candidates for the MCID. These candidates were evaluated by anchoring the NPI-TBI-IA to Global Impression of Change (GIC) ratings by participants, significant others, and a supervising physician. Setting Postacute rehabilitation outpatient clinic. Participants 274 cases with observer ratings; 232 cases with self-ratings by participants with moderate-severe TBI at least 6 months postinjury. Interventions Not applicable. Main Outcome Measure NPI-TBI-IA. Results For observer ratings on the NPI-TBI-IA, anchored comparisons found an improvement of 0.5 SD was associated with at least minimal general improvement on GIC by a significant majority (69%–80%); 0.5 SD improvement on participant NPI-TBI-IA self-ratings was also associated with at least minimal improvement on the GIC by a substantial majority (77%–83%). The percentage indicating significant global improvement did not increase markedly on most ratings at higher levels of improvement on the NPI-TBI-IA. Conclusions A 0.5 SD improvement on the NPI-TBI-IA indicates the MCID for both observer and participant ratings on this measure.en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationMalec, J. F., & Hammond, F. M. (2017). The Minimal Clinically Important Difference for the Rasch Neuropsychiatric Inventory Irritability and Aggression Scale for Traumatic Brain Injury. Archives of Physical Medicine and Rehabilitation. https://doi.org/10.1016/j.apmr.2017.06.038en_US
dc.identifier.urihttps://hdl.handle.net/1805/14499
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.apmr.2017.06.038en_US
dc.relation.journalArchives of Physical Medicine and Rehabilitationen_US
dc.rightsPublisher Policyen_US
dc.sourceAuthoren_US
dc.subjectaggressionen_US
dc.subjectbehavioren_US
dc.subjectbrain injuriesen_US
dc.titleMinimal Clinically Important Difference for the Rasch Neuropsychiatric Inventory Irritability and Aggression Scale for Traumatic Brain Injuryen_US
dc.typeArticleen_US
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