MicroRNA in inflammatory bowel disease: Translational research and clinical implication

Simple item page
dc.contributor.authorFisher, Kurt
dc.contributor.authorLin, Jingmei
dc.contributor.departmentDepartment of Pathology and Laboratory Medicine, IU School of Medicineen_US
dc.date.accessioned2016-10-19T16:21:05Z
dc.date.available2016-10-19T16:21:05Z
dc.date.issued2015-11-21
dc.description.abstractIdiopathic inflammatory bowel disease (IBD) predominantly includes ulcerative colitis and Crohn's disease. The pathogenesis of IBD is complex and not completely understood. MicroRNAs belong to a class of noncoding small RNAs that post-transcriptionally regulate gene expression. Unique microRNA expression profiles have been explored in IBD. In this review, we focus on the unique microRNA expression pattern in both tissue and peripheral blood from IBD patients and emphasize the potential diagnostic and therapeutic applications. The discovery of microRNAs has contributed to our understanding of IBD pathogenesis and might lead to clinical advance in new therapeutics.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationFisher, K., & Lin, J. (2015). MicroRNA in inflammatory bowel disease: Translational research and clinical implication. World Journal of Gastroenterology, 21(43), 12274–12282. http://doi.org/10.3748/wjg.v21.i43.12274en_US
dc.identifier.urihttps://hdl.handle.net/1805/11183
dc.language.isoen_USen_US
dc.publisherBaishideng Publishing Group Coen_US
dc.relation.isversionof10.3748/wjg.v21.i43.12274en_US
dc.relation.journalWorld Journal of Gastroenterologyen_US
dc.rightsAttribution-NonCommercial 3.0 United States
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/us
dc.sourcePMCen_US
dc.subjectCrohn’s diseaseen_US
dc.subjectGene expressionen_US
dc.subjectInflammatory bowel diseaseen_US
dc.subjectMicroRNAen_US
dc.subjectPathogenesisen_US
dc.subjectUlcerative colitisen_US
dc.titleMicroRNA in inflammatory bowel disease: Translational research and clinical implicationen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
WJG-21-12274.pdf
Size:
837.08 KB
Format:
Adobe Portable Document Format
Description:
Final published version
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.88 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Open Access Policy Articles
Department of Pathology and Laboratory Medicine Works