Real world performance of the 21st Century Cures Act population-level application programming interface

dc.contributor.authorJones, James R.
dc.contributor.authorGottlieb, Daniel
dc.contributor.authorMcMurry, Andrew J.
dc.contributor.authorAtreja, Ashish
dc.contributor.authorDesai, Pankaja M.
dc.contributor.authorDixon, Brian E.
dc.contributor.authorPayne, Philip R. O.
dc.contributor.authorSaldanha, Anil J.
dc.contributor.authorShankar, Prabhu
dc.contributor.authorSolad, Yauheni
dc.contributor.authorWilcox, Adam B.
dc.contributor.authorAli, Momeena S.
dc.contributor.authorKang, Eugene
dc.contributor.authorMartin, Andrew M.
dc.contributor.authorSprouse, Elizabeth
dc.contributor.authorTaylor, David E.
dc.contributor.authorTerry, Michael
dc.contributor.authorIgnatov, Vladimir
dc.contributor.authorMandl, Kenneth D.
dc.contributor.departmentHealth Policy and Management, Richard M. Fairbanks School of Public Health
dc.date.accessioned2025-04-18T13:16:59Z
dc.date.available2025-04-18T13:16:59Z
dc.date.issued2024
dc.description.abstractObjective: To evaluate the real-world performance of the SMART/HL7 Bulk Fast Health Interoperability Resources (FHIR) Access Application Programming Interface (API), developed to enable push button access to electronic health record data on large populations, and required under the 21st Century Cures Act Rule. Materials and methods: We used an open-source Bulk FHIR Testing Suite at 5 healthcare sites from April to September 2023, including 4 hospitals using electronic health records (EHRs) certified for interoperability, and 1 Health Information Exchange (HIE) using a custom, standards-compliant API build. We measured export speeds, data sizes, and completeness across 6 types of FHIR. Results: Among the certified platforms, Oracle Cerner led in speed, managing 5-16 million resources at over 8000 resources/min. Three Epic sites exported a FHIR data subset, achieving 1-12 million resources at 1555-2500 resources/min. Notably, the HIE's custom API outperformed, generating over 141 million resources at 12 000 resources/min. Discussion: The HIE's custom API showcased superior performance, endorsing the effectiveness of SMART/HL7 Bulk FHIR in enabling large-scale data exchange while underlining the need for optimization in existing EHR platforms. Agility and scalability are essential for diverse health, research, and public health use cases. Conclusion: To fully realize the interoperability goals of the 21st Century Cures Act, addressing the performance limitations of Bulk FHIR API is critical. It would be beneficial to include performance metrics in both certification and reporting processes.
dc.eprint.versionFinal published version
dc.identifier.citationJones JR, Gottlieb D, McMurry AJ, et al. Real world performance of the 21st Century Cures Act population-level application programming interface. J Am Med Inform Assoc. 2024;31(5):1144-1150. doi:10.1093/jamia/ocae040
dc.identifier.urihttps://hdl.handle.net/1805/47179
dc.language.isoen_US
dc.publisherOxford University Press
dc.relation.isversionof10.1093/jamia/ocae040
dc.relation.journalJournal of the American Medical Informatics Association
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectComputerized
dc.subjectHealth information interoperability
dc.subjectHealth information systems
dc.subjectMedical informatics
dc.subjectMedical records systems
dc.subjectPublic health informatics
dc.titleReal world performance of the 21st Century Cures Act population-level application programming interface
dc.typeArticle
ul.alternative.fulltexthttps://pmc.ncbi.nlm.nih.gov/articles/PMC11031206/
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