Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement From the American Heart Association

dc.contributor.authorLandstrom, Andrew P.
dc.contributor.authorKim, Jeffrey J.
dc.contributor.authorGelb, Bruce D.
dc.contributor.authorHelm, Benjamin M.
dc.contributor.authorKannankeril, Prince J.
dc.contributor.authorSemsarian, Christopher
dc.contributor.authorSturm, Amy C.
dc.contributor.authorTristani-Firouzi, Martin
dc.contributor.authorWare, Stephanie M.
dc.contributor.departmentMedical and Molecular Genetics, School of Medicine
dc.date.accessioned2024-10-18T08:48:44Z
dc.date.available2024-10-18T08:48:44Z
dc.date.issued2021
dc.description.abstractGenetic diseases that affect the cardiovascular system are relatively common and include cardiac channelopathies, cardiomyopathies, aortopathies, hypercholesterolemias, and structural diseases of the heart and great vessels. The rapidly expanding availability of clinical genetic testing leverages decades of research into the genetic origins of these diseases, helping inform diagnosis, clinical management, and prognosis. Although a number of guidelines and statements detail best practices for cardiovascular genetic testing, there is a paucity of pediatric-focused statements addressing the unique challenges in testing in this vulnerable population. In this scientific statement, we seek to coalesce the existing literature around the use of genetic testing for cardiovascular disease in infants, children, and adolescents.
dc.eprint.versionAuthor's manuscript
dc.identifier.citationLandstrom AP, Kim JJ, Gelb BD, et al. Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement From the American Heart Association. Circ Genom Precis Med. 2021;14(5):e000086. doi:10.1161/HCG.0000000000000086
dc.identifier.urihttps://hdl.handle.net/1805/44056
dc.language.isoen_US
dc.publisherAmerican Heart Association
dc.relation.isversionof10.1161/HCG.0000000000000086
dc.relation.journalCirculation: Genomic and Precision Medicine
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectAHA Scientific Statements
dc.subjectCardiomyopathies
dc.subjectChannelopathies
dc.subjectConnective tissue diseases
dc.subjectCounseling
dc.subjectGenetic
dc.subjectPredictive genetic testing
dc.titleGenetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement From the American Heart Association
dc.typeArticle
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