The Cardiopulmonary Complications of Sickle Cell Disease
dc.contributor.author | Desai, Ankit A. | |
dc.contributor.author | Machado, Roberto F. | |
dc.contributor.author | Cohen, Robyn T. | |
dc.contributor.department | Medicine, School of Medicine | |
dc.date.accessioned | 2024-02-08T18:01:07Z | |
dc.date.available | 2024-02-08T18:01:07Z | |
dc.date.issued | 2022 | |
dc.description.abstract | Sickle cell disease (SCD) is a genetic hemoglobinopathy associated with extensive morbidity and early mortality. While there have been recent improvements in available disease-modifying therapies for SCD, cardiopulmonary complications remain a major risk factor for death in this population. We provide an overview of current knowledge regarding several of the major acute and chronic cardiopulmonary complications in SCD, including: acute chest syndrome, airway disease, lung function abnormalities, nocturnal hypoxemia and sleep disordered breathing, pulmonary vascular disease, and sickle cell cardiomyopathy. | |
dc.eprint.version | Author's manuscript | |
dc.identifier.citation | Desai AA, Machado RF, Cohen RT. The Cardiopulmonary Complications of Sickle Cell Disease. Hematol Oncol Clin North Am. 2022;36(6):1217-1237. doi:10.1016/j.hoc.2022.07.014 | |
dc.identifier.uri | https://hdl.handle.net/1805/38338 | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | |
dc.relation.isversionof | 10.1016/j.hoc.2022.07.014 | |
dc.relation.journal | Hematology/Oncology Clinics of North America | |
dc.rights | Publisher Policy | |
dc.source | PMC | |
dc.subject | Acute chest syndrome | |
dc.subject | Lung function | |
dc.subject | Pulmonary hypertension | |
dc.subject | Sickle cell cardiomyopathy | |
dc.subject | Sickle cell disease | |
dc.subject | Sleep-disordered breathing | |
dc.title | The Cardiopulmonary Complications of Sickle Cell Disease | |
dc.type | Article |