Myocardial extracellular volume measurement using cardiac computed tomography

dc.contributor.authorMuthalaly, Rahul G.
dc.contributor.authorAbrahams, Timothy
dc.contributor.authorLin, Andrew
dc.contributor.authorPatel, Kush
dc.contributor.authorTan, Sean
dc.contributor.authorDey, Damini
dc.contributor.authorHan, Donghee
dc.contributor.authorTamarappoo, Balaji K.
dc.contributor.authorNicholls, Stephen J
dc.contributor.authorNerlekar, Nitesh
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2024-12-13T08:56:47Z
dc.date.available2024-12-13T08:56:47Z
dc.date.issued2024
dc.description.abstractMyocardial fibrosis is a common endpoint of many cardiac diseases and increasingly recognized as a predictor of heart failure, arrhythmia, and death. Recent studies have utilised cardiac computed tomography (CT) scans with delayed phase imaging to quantify diffuse fibrosis of the myocardium. CT extracellular volume (CT-ECV) measurement correlates well with CMR and histological myocardial fibrosis. Furthermore, CT-ECV predicts outcomes such as death, heart failure and arrhythmia in various disease states. This review summarizes the rationale and methodology behind CT-ECV measurement and provides a detailed summary of the current clinical evidence for the use of CT-ECV.
dc.eprint.versionFinal published version
dc.identifier.citationMuthalaly RG, Abrahams T, Lin A, et al. Myocardial extracellular volume measurement using cardiac computed tomography. Int J Cardiovasc Imaging. 2024;40(11):2237-2245. doi:10.1007/s10554-024-03226-4
dc.identifier.urihttps://hdl.handle.net/1805/45001
dc.language.isoen_US
dc.publisherSpringer
dc.relation.isversionof10.1007/s10554-024-03226-4
dc.relation.journalThe International Journal of Cardiovascular Imaging
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.sourcePMC
dc.subjectCardiomyopathies
dc.subjectFibrosis
dc.subjectMultidetector computed tomography
dc.subjectMyocardium
dc.titleMyocardial extracellular volume measurement using cardiac computed tomography
dc.typeArticle
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