Turning the clock forward: Inflammation accelerates the aging of hematopoietic stem cells
| dc.contributor.author | Burns, Sarah S. | |
| dc.contributor.author | Kapur, Reuben | |
| dc.contributor.department | Pediatrics, School of Medicine | |
| dc.date.accessioned | 2023-10-16T11:51:28Z | |
| dc.date.available | 2023-10-16T11:51:28Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | In the current issue of Cell Stem Cell, Bogeska et al. demonstrate that repeated exposures to inflammation cause indelible and specific functional compromise and accelerated aging of long-term hematopoietic stem cells (LT-HSCs). This study proposes the notion that the cumulative inflammatory events over the course of an organism's lifespan may irreversibly damage LT-HSCs. | |
| dc.eprint.version | Author's manuscript | |
| dc.identifier.citation | Burns SS, Kapur R. Turning the clock forward: Inflammation accelerates the aging of hematopoietic stem cells. Cell Stem Cell. 2022;29(8):1156-1158. doi:10.1016/j.stem.2022.07.002 | |
| dc.identifier.uri | https://hdl.handle.net/1805/36310 | |
| dc.language.iso | en_US | |
| dc.publisher | Elsevier | |
| dc.relation.isversionof | 10.1016/j.stem.2022.07.002 | |
| dc.relation.journal | Cell Stem Cell | |
| dc.rights | Publisher Policy | |
| dc.source | PMC | |
| dc.subject | Aging | |
| dc.subject | Hematopoietic stem cells | |
| dc.subject | Inflammation | |
| dc.title | Turning the clock forward: Inflammation accelerates the aging of hematopoietic stem cells | |
| dc.type | Article |