Releasing the brakes: a case report of pulmonary arterial hypertension induced by immune checkpoint inhibitor therapy

dc.contributor.authorGlick, Matthew
dc.contributor.authorBaxter, Chase
dc.contributor.authorLopez, David
dc.contributor.authorMufti, Kashif
dc.contributor.authorSawada, Stephen
dc.contributor.authorLahm, Tim
dc.contributor.departmentMedicine, School of Medicineen_US
dc.date.accessioned2022-01-10T19:31:51Z
dc.date.available2022-01-10T19:31:51Z
dc.date.issued2020-10
dc.description.abstractImmune checkpoint inhibitors successfully treat various malignancies by inducing an immune response to tumor cells. However, their use has been associated with a variety of autoimmune disorders, such as diabetes, hepatitis, and pneumonitis. Pulmonary arterial hypertension due to checkpoint inhibitor use has not yet been described. We present a novel case of pulmonary arterial hypertension associated with systemic lupus erythematosus and Sjogren’s syndrome overlap that was induced by therapy with the checkpoint inhibitor durvalumab.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationGlick, M., Baxter, C., Lopez, D., Mufti, K., Sawada, S., & Lahm, T. (2020). Releasing the brakes: A case report of pulmonary arterial hypertension induced by immune checkpoint inhibitor therapy. Pulmonary Circulation, 10(4), 1–4. https://doi.org/10.1177/2045894020960967en_US
dc.identifier.issn2045-8940, 2045-8940en_US
dc.identifier.urihttps://hdl.handle.net/1805/27337
dc.language.isoen_USen_US
dc.publisherWileyen_US
dc.relation.isversionof10.1177/2045894020960967en_US
dc.relation.journalPulmonary Circulationen_US
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0*
dc.sourcePublisheren_US
dc.subjectautoimmune diseaseen_US
dc.subjectdurvalumaben_US
dc.subjectimmunotherapyen_US
dc.subjectprogrammed death-ligand 1 inhibitoren_US
dc.subjectright heart failureen_US
dc.titleReleasing the brakes: a case report of pulmonary arterial hypertension induced by immune checkpoint inhibitor therapyen_US
dc.typeArticleen_US
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