Releasing the brakes: a case report of pulmonary arterial hypertension induced by immune checkpoint inhibitor therapy
dc.contributor.author | Glick, Matthew | |
dc.contributor.author | Baxter, Chase | |
dc.contributor.author | Lopez, David | |
dc.contributor.author | Mufti, Kashif | |
dc.contributor.author | Sawada, Stephen | |
dc.contributor.author | Lahm, Tim | |
dc.contributor.department | Medicine, School of Medicine | en_US |
dc.date.accessioned | 2022-01-10T19:31:51Z | |
dc.date.available | 2022-01-10T19:31:51Z | |
dc.date.issued | 2020-10 | |
dc.description.abstract | Immune checkpoint inhibitors successfully treat various malignancies by inducing an immune response to tumor cells. However, their use has been associated with a variety of autoimmune disorders, such as diabetes, hepatitis, and pneumonitis. Pulmonary arterial hypertension due to checkpoint inhibitor use has not yet been described. We present a novel case of pulmonary arterial hypertension associated with systemic lupus erythematosus and Sjogren’s syndrome overlap that was induced by therapy with the checkpoint inhibitor durvalumab. | en_US |
dc.eprint.version | Final published version | en_US |
dc.identifier.citation | Glick, M., Baxter, C., Lopez, D., Mufti, K., Sawada, S., & Lahm, T. (2020). Releasing the brakes: A case report of pulmonary arterial hypertension induced by immune checkpoint inhibitor therapy. Pulmonary Circulation, 10(4), 1–4. https://doi.org/10.1177/2045894020960967 | en_US |
dc.identifier.issn | 2045-8940, 2045-8940 | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/27337 | |
dc.language.iso | en_US | en_US |
dc.publisher | Wiley | en_US |
dc.relation.isversionof | 10.1177/2045894020960967 | en_US |
dc.relation.journal | Pulmonary Circulation | en_US |
dc.rights | Attribution-NonCommercial 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0 | * |
dc.source | Publisher | en_US |
dc.subject | autoimmune disease | en_US |
dc.subject | durvalumab | en_US |
dc.subject | immunotherapy | en_US |
dc.subject | programmed death-ligand 1 inhibitor | en_US |
dc.subject | right heart failure | en_US |
dc.title | Releasing the brakes: a case report of pulmonary arterial hypertension induced by immune checkpoint inhibitor therapy | en_US |
dc.type | Article | en_US |