Synthesis of Natural Homoisoflavonoids Having Either 5,7-Dihydroxy-6-methoxy or 7-Hydroxy-5,6-dimethoxy Groups
| dc.contributor.author | Lee, Hyungjun | |
| dc.contributor.author | Yuan, Yue | |
| dc.contributor.author | Rhee, Inmoo | |
| dc.contributor.author | Corson, Timothy W. | |
| dc.contributor.author | Seo, Seung-Yong | |
| dc.contributor.department | Department of Ophthalmology, IU School of Medicine | en_US |
| dc.date.accessioned | 2017-05-26T16:10:20Z | |
| dc.date.available | 2017-05-26T16:10:20Z | |
| dc.date.issued | 2016-08 | |
| dc.description.abstract | Naturally occurring homoisoflavonoids containing either 5,7-dihydroxy-6-methoxy or 7-hydroxy-5,6-dimethoxy groups such as the antiangiogenic homoisoflavanone, cremastranone, were synthesized via three or four linear steps from the known 4-chromenone. This facile synthesis includes chemoselective 1,4-reduction of 4-chromenone and selective deprotection of 3-benzylidene-4-chromanone a containing C7-benzyloxy group. | en_US |
| dc.eprint.version | Final published version | en_US |
| dc.identifier.citation | Lee H, Yuan Y, Rhee I, Corson TW, Seo SY. 2016. Synthesis of natural homoisoflavonoids having either 5,7-dihydroxy-6-methoxy or 7-hydroxy-5,6-dimethoxy groups. Molecules, 21, 1058. http://dx.doi.org/10.3390/molecules21081058 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1805/12750 | |
| dc.language.iso | en | en_US |
| dc.publisher | MDPI | en_US |
| dc.relation.isversionof | 10.3390/molecules21081058 | en_US |
| dc.relation.journal | Molecules | en_US |
| dc.rights | Attribution 3.0 United States | |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | |
| dc.source | Publisher | en_US |
| dc.subject | homoisoflavonoids | en_US |
| dc.subject | cremastranone | en_US |
| dc.subject | 4-chromanone | en_US |
| dc.title | Synthesis of Natural Homoisoflavonoids Having Either 5,7-Dihydroxy-6-methoxy or 7-Hydroxy-5,6-dimethoxy Groups | en_US |
| dc.type | Article | en_US |