Interventions to improve the physical function of ICU survivors: a systematic review
dc.contributor.author | Calvo-Ayala, Enrique | |
dc.contributor.author | Khan, Babar A. | |
dc.contributor.author | Farber, Mark O. | |
dc.contributor.author | Ely, E. Wesley | |
dc.contributor.author | Boustani, Malaz A. | |
dc.contributor.department | Medicine, School of Medicine | en_US |
dc.date.accessioned | 2015-09-15T19:03:48Z | |
dc.date.available | 2015-09-15T19:03:48Z | |
dc.date.issued | 2013-11 | |
dc.description.abstract | BACKGROUND: ICU admissions are ever increasing across the United States. Following critical illness, physical functioning (PF) may be impaired for up to 5 years. We performed a systematic review of randomized controlled trials evaluating the efficacy of interventions targeting PF among ICU survivors. The objective of this study was to identify effective interventions that improve long-term PF in ICU survivors. METHODS: MEDLINE, Excerpta Medica Database (EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Physiotherapy Evidence-Based Database (PEDro) were searched between 1990 and 2012. Two reviewers independently evaluated studies for eligibility, critically appraised the included studies, and extracted data into standardized evidence tables. RESULTS: Fourteen studies met the inclusion criteria. Interventions included exercise/physical therapy (PT), parenteral nutrition, nurse-led follow-up, spontaneous awakening trials, absence of sedation during mechanical ventilation, and early tracheotomy. Nine studies failed to demonstrate efficacy on PF of the ICU survivors. However, early physical exercise and PT-based interventions had a positive effect on long-term PF. CONCLUSIONS: The only effective intervention to improve long-term PF in critically ill patients is exercise/PT; its benefit may be greater if started earlier. Further research in this area comparing different interventions and timing is needed. | en_US |
dc.identifier.citation | Calvo-Ayala, E., Khan, B. A., Farber, M. O., Ely, E. W., & Boustani, M. A. (2013). Interventions to Improve the Physical Function of ICU Survivors: A Systematic Review. Chest, 144(5), 1469–1480. http://doi.org/10.1378/chest.13-0779 | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/6942 | |
dc.language.iso | en_US | en_US |
dc.publisher | American College of Chest Physicians | en_US |
dc.relation.isversionof | 10.1378/chest.13-0779 | en_US |
dc.relation.journal | Chest | en_US |
dc.rights | Publisher Policy | en_US |
dc.source | PMC | en_US |
dc.subject | Critical Illness -- therapy | en_US |
dc.subject | Exercise Therapy -- methods | en_US |
dc.subject | Humans | en_US |
dc.subject | Intensive Care Units | en_US |
dc.subject | Quality of Life | en_US |
dc.title | Interventions to improve the physical function of ICU survivors: a systematic review | en_US |
dc.type | Article | en_US |
ul.alternative.fulltext | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817929/ | en_US |
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