Large-bore aspiration thrombectomy for the treatment of pulmonary embolism in octogenarians
dc.contributor.author | Masterson, Reid | |
dc.contributor.author | Pebror, Travis | |
dc.contributor.author | Gauger, Andrew | |
dc.contributor.author | Schmitz, Adam William | |
dc.contributor.author | Butty, Sabah David | |
dc.contributor.department | Radiology and Imaging Sciences, School of Medicine | |
dc.date.accessioned | 2025-02-17T17:13:52Z | |
dc.date.available | 2025-02-17T17:13:52Z | |
dc.date.issued | 2025-01-22 | |
dc.description.abstract | Purpose: To evaluate outcomes in patients aged ≥ 80 years following large-bore aspiration thrombectomy (LBAT) for the treatment of pulmonary embolism (PE). Materials and methods: All patients ≥ 80 years of age with PE treated via LBAT at a single center were analyzed from September 2019 - August 2024. This included the octogenarian subgroup from a recently published retrospective analysis assessing all PE patients treated with LBAT at our center between September 2019 and January 2023. The following outcomes were evaluated: technical success, change in several hemodynamic measures including pulmonary artery pressure (PAP) and right ventricle to left ventricle ratio (RV to LV ratio), length of hospital and intensive-care-unit (ICU) stay, procedure-related complications, and 7- and 30-day mortality. Results: Forty-eight patients aged ≥ 80 years underwent LBAT procedures for PE. Technical success was achieved in 46 cases (95.8%). The mean reduction in mean PAP was 3.6 mmHg. The mean reduction in RV to LV ratio was -0.42. The mean length of postprocedural hospital and ICU stays were 5.7 ± 3.6 days and 1.0 ± 1.6 days, respectively. There were 2 procedural complications, 1 pulmonary vascular injury involving a pulmonary artery pseudoaneurysm and 1 decompensation involving hypotension requiring vasopressor support. There were no major bleeding complications or cardiac injuries. All-cause mortality was 2.1% (n = 1) at 7 days and 6.3% (n = 3) at 30 days post procedure. PE-related mortality was 2.1% (n = 1) at 30 days. Conclusion: LBAT is a technically feasible procedure for the treatment of PE in octogenarian patients and has a favorable preliminary safety and mortality profile. | |
dc.eprint.version | Final published version | |
dc.identifier.citation | Masterson R, Pebror T, Gauger A, Schmitz AW, Butty SD. Large-bore aspiration thrombectomy for the treatment of pulmonary embolism in octogenarians. CVIR Endovasc. 2025;8(1):7. Published 2025 Jan 22. doi:10.1186/s42155-025-00517-2 | |
dc.identifier.uri | https://hdl.handle.net/1805/45747 | |
dc.language.iso | en_US | |
dc.publisher | Springer | |
dc.relation.isversionof | 10.1186/s42155-025-00517-2 | |
dc.relation.journal | CVIR Endovascular | |
dc.rights | Attribution 4.0 International | en |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.source | PMC | |
dc.subject | Octogenarian | |
dc.subject | Advanced age | |
dc.subject | Pulmonary embolism | |
dc.subject | Thrombectomy | |
dc.subject | Reperfusion therapy | |
dc.title | Large-bore aspiration thrombectomy for the treatment of pulmonary embolism in octogenarians | |
dc.type | Article |