Decreasing Delirium Through Music: A Randomized Pilot Trial

dc.contributor.authorKhan, Sikandar H.
dc.contributor.authorXu, Chenjia
dc.contributor.authorPurpura, Russell
dc.contributor.authorDurrani, Sana
dc.contributor.authorLindroth, Heidi
dc.contributor.authorWang, Sophia
dc.contributor.authorGao, Sujuan
dc.contributor.authorHeiderscheit, Annie
dc.contributor.authorChlan, Linda
dc.contributor.authorBoustani, Malaz
dc.contributor.authorKhan, Babar A.
dc.contributor.departmentMedicine, School of Medicineen_US
dc.description.abstractBackground: Management of delirium in intensive care units is challenging because effective therapies are lacking. Music is a promising nonpharmacological intervention. Objectives: To determine the feasibility and acceptability of personalized music (PM), slow-tempo music (STM), and attention control (AC) in patients receiving mechanical ventilation in an intensive care unit, and to estimate the effect of music on delirium. Methods: A randomized controlled trial was performed in an academic medical-surgical intensive care unit. After particular inclusion and exclusion criteria were applied, patients were randomized to groups listening to PM, relaxing STM, or an audiobook (AC group). Sessions lasted 1 hour and were given twice daily for up to 7 days. Patients wore noise-canceling headphones and used mp3 players to listen to their music/audiobook. Delirium and delirium severity were assessed twice daily by using the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and the CAM-ICU-7, respectively. Results: Of the 1589 patients screened, 117 (7.4%) were eligible. Of those, 52 (44.4%) were randomized, with a recruitment rate of 5 patients per month. Adherence was higher in the groups listening to music (80% in the PM and STM groups vs 30% in the AC group; P = .01), and 80% of patients surveyed rated the music as enjoyable. The median number (interquartile range) of delirium/coma-free days by day 7 was 2 (1-6) for PM, 3 (1-6) for STM, and 2 (0-3) for AC (P = .32). Median delirium severity was 5.5 (1-7) for PM, 3.5 (0-7) for STM, and 4 (1-6.5) for AC (P = .78). Conclusions: Music delivery is acceptable to patients and is feasible in intensive care units. Further research testing use of this promising intervention to reduce delirium is warranted.en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationKhan SH, Xu C, Purpura R, et al. Decreasing Delirium Through Music: A Randomized Pilot Trial. Am J Crit Care. 2020;29(2):e31-e38. doi:10.4037/ajcc2020175en_US
dc.publisherAmerican Association of Critical-Care Nursesen_US
dc.relation.journalAmerican Journal of Critical Careen_US
dc.rightsPublisher Policyen_US
dc.subjectIntensive Care Unitsen_US
dc.subjectMusic therapyen_US
dc.subjectSingle-blind methoden_US
dc.titleDecreasing Delirium Through Music: A Randomized Pilot Trialen_US
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
426.39 KB
Adobe Portable Document Format
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
1.99 KB
Item-specific license agreed upon to submission