Retraction Note: REST regulates the cell cycle for cardiac development and regeneration

Abstract

Retraction to: Nature Communications 10.1038/s41467-017-02210-y, published online 07 December 2017

The authors have retracted this article because of significant concerns regarding a number of figures presented in this work that question the integrity of the data. After publication, several concerns were raised about the figures in this article.

Specifically,

* There appears to be a partial overlap between two panels of Figure 4e (bottom left corner for p21KO and top right for DKO). * There appears to be an overlap between a control panel from figure 2k and Rest imKO in Figure 5g (PH3 staining). * There appears to be image reuse between two samples in Figure 5g in the Aurora B staining row for Rest imKO and p21KO. * There appears to be an overlap between Figure 6f Ph3 staining for the Rest cDNA sample and Supplementary Fig. 6e, EdU staining, Rest cDNA, with fewer arrows and less visible DAPI staining.

All authors agree with this retraction.