Alcoholic-induced hepatic steatosis – role of ceramide and protein phosphatase 2A
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2011
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American English
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Elsevier
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Abstract
The mechanisms underlying alcohol-induced hepatic steatosis are complex, involving the disturbance of several signaling pathways. We have gained a better understanding of the role of the innate immune system in the liver and its effects on lipid metabolism and uncovered a number of circulating factors that can influence the response of the liver to ethanol. In this report, we will focus on the potential role of ceramide on AMP-activated protein kinase, as a mediator of alcohol-induced hepatic steatosis.
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Cite As
Supakul R, Liangpunsakul S. Alcoholic-induced hepatic steatosis--role of ceramide and protein phosphatase 2A. Transl Res. 2011;158(2):77-81. doi:10.1016/j.trsl.2011.03.005
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Translational Research
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