IgA Nephropathy in the Setting of Anti-TNF-α Therapy for Inflammatory Bowel Disease
dc.contributor.author | Strobel, Thomas | |
dc.contributor.author | Ahmed, Waseem | |
dc.contributor.author | De la Sancha, Carlo | |
dc.contributor.author | Bohm, Matthew | |
dc.contributor.author | Fischer, Monika | |
dc.contributor.department | Medicine, School of Medicine | en_US |
dc.date.accessioned | 2021-08-09T20:58:32Z | |
dc.date.available | 2021-08-09T20:58:32Z | |
dc.date.issued | 2020-09-01 | |
dc.description.abstract | Tumor necrosis factor-α (TNF-α)-inhibiting agents are a standard therapy for moderate-to-severe inflammatory bowel disease (IBD). IgA nephropathy in the setting of prolonged exposure to TNF-α inhibitors is a rare, clinically significant adverse event often overlooked by gastroenterologists but well documented in the rheumatologic literature. We present a case series of 3 patients with IBD on TNF-α inhibitors who developed biopsy-proven IgA nephropathy. Clinicians prescribing TNF-α inhibitors to patients with IBD need to be aware of this potential side effect. Therapies with alternative mechanisms of action should instead be considered. | en_US |
dc.identifier.citation | Strobel, T., Ahmed, W., De la Sancha, C., Bohm, M., & Fischer, M. (2020). IgA Nephropathy in the Setting of Anti-TNF-α Therapy for Inflammatory Bowel Disease. ACG Case Reports Journal, 7(9), e00462. https://doi.org/10.14309/crj.0000000000000462 | en_US |
dc.identifier.issn | 2326-3253 | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/26411 | |
dc.language.iso | en_US | en_US |
dc.publisher | Wolters Kluwer | en_US |
dc.relation.isversionof | 10.14309/crj.0000000000000462 | en_US |
dc.relation.journal | ACG Case Reports Journal | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.source | PMC | en_US |
dc.subject | Tumor necrosis factor-α | en_US |
dc.subject | inflammatory bowel disease | en_US |
dc.subject | Crohn's disease | en_US |
dc.subject | gastrointestinal tract | en_US |
dc.subject | ulcerative colitis | en_US |
dc.title | IgA Nephropathy in the Setting of Anti-TNF-α Therapy for Inflammatory Bowel Disease | en_US |
dc.type | Article | en_US |