A 61-year-old woman with osteomalacia and a thoracic spine lesion

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2010-03
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American English
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Wiley
Abstract

Phosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia. It is generally found in the soft tissue and bone of the extremities. We report a case of a 61-year-old female with long-standing osteomalacia who was found to have PMT-MCT of the thoracic spine. There have been very few previously reported cases of PMT involving the spinal vertebrae and neuropathologists should be aware of this lesion. Recognition of PMT-MCT is critical for optimal patient care since complete surgical resection without additional therapy is curative.

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Marshall AE, Martin SE, Agaram NP, et al. A 61-year-old woman with osteomalacia and a thoracic spine lesion. Brain Pathol. 2010;20(2):499-502. doi:10.1111/j.1750-3639.2009.00360.x
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Brain Pathology
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PMC
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