Mechanistic Observations on the Role of the Stannous Ion in Caries Lesion De- and Remineralization
dc.contributor.author | Lippert, Frank | |
dc.contributor.department | Department of Cariology, Operative Dentistry and Dental Public Health, School of Dentistry | en_US |
dc.date.accessioned | 2017-08-18T14:51:53Z | |
dc.date.available | 2017-08-18T14:51:53Z | |
dc.date.issued | 2016-09 | |
dc.description.abstract | Two mechanistic, laboratory, factorial design studies were conducted to investigate the effect of the stannous ion (Sn2+) in the absence or presence of fluoride on caries lesion de- and remineralization. Study I was concerned with determining changes in mineral distribution of subsurface lesions, whereas study II investigated changes in surface hardness of surface-softened lesions as a function of pH. Study I showed that Sn2+ modulates the effects of fluoride by preventing lamination. Study II revealed that the effect of Sn2+ on rehardening is pH dependent. Neither study demonstrated synergy between Sn2+ and fluoride, yet interactions were observed. Sn2+ does interfere with remineralization to some extent although it provided acid resistance. The role of Sn2+ in the caries process is complex. | en_US |
dc.eprint.version | Final published version | en_US |
dc.identifier.citation | Lippert, F. (2016). Mechanistic Observations on the Role of the Stannous Ion in Caries Lesion De-and Remineralization. Caries research, 50(4), 378-382. | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/13863 | |
dc.language.iso | en | en_US |
dc.publisher | Karger | en_US |
dc.relation.isversionof | 10.1159/000446849 | en_US |
dc.relation.journal | Caries Research | en_US |
dc.rights | Publisher Policy | en_US |
dc.source | Author | en_US |
dc.subject | caries | en_US |
dc.subject | demineralization | en_US |
dc.subject | enamel | en_US |
dc.title | Mechanistic Observations on the Role of the Stannous Ion in Caries Lesion De- and Remineralization | en_US |
dc.type | Article | en_US |
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