SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells
dc.contributor.author | Zhong, Xiaolin | |
dc.contributor.author | Huang, Menghao | |
dc.contributor.author | Kim, Hyeong-Geug | |
dc.contributor.author | Zhang, Yang | |
dc.contributor.author | Chowdhury, Kushan | |
dc.contributor.author | Cai, Wenjie | |
dc.contributor.author | Saxena, Romil | |
dc.contributor.author | Schwabe, Robert F. | |
dc.contributor.author | Liangpunsakul, Suthat | |
dc.contributor.author | Dong, X. Charlie | |
dc.contributor.department | Biochemistry and Molecular Biology, School of Medicine | en_US |
dc.date.accessioned | 2020-11-18T16:25:00Z | |
dc.date.available | 2020-11-18T16:25:00Z | |
dc.date.issued | 2020-04-17 | |
dc.identifier.citation | Zhong, X., Huang, M., Kim, H.-G., Zhang, Y., Chowdhury, K., Cai, W., Saxena, R., Schwabe, R. F., Liangpunsakul, S., & Dong, X. C. (2020). SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells. Cellular and Molecular Gastroenterology and Hepatology, 10(2), 341–364. https://doi.org/10.1016/j.jcmgh.2020.04.005 | en_US |
dc.identifier.issn | 2352-345X | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/24446 | |
dc.language.iso | en_US | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.isversionof | 10.1016/j.jcmgh.2020.04.005 | en_US |
dc.relation.journal | Cellular and Molecular Gastroenterology and Hepatology | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0 | * |
dc.source | PMC | en_US |
dc.subject | alanine aminotransferase | en_US |
dc.subject | chromatin immunoprecipitation | en_US |
dc.subject | Dulbecco’s modified Eagle medium | en_US |
dc.subject | green fluorescent protein | en_US |
dc.subject | hemagglutinin | en_US |
dc.subject | hepatic stellate cell | en_US |
dc.subject | KO knockout | en_US |
dc.subject | Lratlecithin retinol acyl | en_US |
dc.subject | transferasem | en_US |
dc.subject | RNA messenger | en_US |
dc.subject | NAFLD nonalcoholic fatty liver disease | en_US |
dc.subject | NASH nonalcoholic steatohepatitis | en_US |
dc.subject | PBS phosphate-buffered saline | en_US |
dc.subject | PCR polymerase chain reactions | en_US |
dc.subject | hRNA short hairpin RNA | en_US |
dc.subject | SIRT6 sirtuin 6 | en_US |
dc.subject | SMAD3 SMAD family member 3 | en_US |
dc.subject | transgenic | en_US |
dc.subject | transforming growth factor β | en_US |
dc.subject | Western diet | en_US |
dc.subject | wild-type | en_US |
dc.title | SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells | en_US |
dc.type | Article | en_US |
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