Immune evasion of the CD1d/NKT cell axis
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Date
2018-06
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American English
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Elsevier
Abstract
Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity. In contrast, here, we discuss the ways that viruses, bacteria and tumor cells can evade the CD1d/NKT cell axis. As a result, these disease states have a better chance to establish a foothold and potentially cause problems for the subsequent adaptive immune response, as the host tries to rid itself of infections or tumors.
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Brutkiewicz, R. R., Yunes-Medina, L., & Liu, J. (2018). Immune evasion of the CD1d/NKT cell axis. Current opinion in immunology, 52, 87–92. doi:10.1016/j.coi.2018.04.021
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Current Opinion in Immunology
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PMC
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Article
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