Evaluation of real-world referential and probabilistic patient matching to advance patient identification strategy

dc.contributor.authorGrannis, Shaun J.
dc.contributor.authorWilliams, Jennifer L.
dc.contributor.authorKasthuri, Suranga
dc.contributor.authorMurray, Molly
dc.contributor.authorXu, Huiping
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2023-08-01T13:45:39Z
dc.date.available2023-08-01T13:45:39Z
dc.date.issued2022
dc.description.abstractObjective: This study sought both to support evidence-based patient identity policy development by illustrating an approach for formally evaluating operational matching methods, and also to characterize the performance of both referential and probabilistic patient matching algorithms using real-world demographic data. Materials and methods: We assessed matching accuracy for referential and probabilistic matching algorithms using a manually reviewed 30 000 record gold standard reference dataset derived from a large health information exchange containing over 47 million patient registrations. We applied referential and probabilistic algorithms to this dataset and compared the outputs to the gold standard. We computed performance metrics including sensitivity (recall), positive predictive value (precision), and F-score for each algorithm. Results: The probabilistic algorithm exhibited sensitivity, positive predictive value (PPV), and F-score of .6366, 0.9995, and 0.7778, respectively. The referential algorithm exhibited corresponding sensitivity, PPV, and F-score values of 0.9351, 0.9996, and 0.9663, respectively. Treating discordant and limited-data records as nonmatches increased referential match sensitivity to 0.9578. Compared to the more traditional probabilistic approach, referential matching exhibits greater accuracy. Conclusions: Referential patient matching, an increasingly popular method among health IT vendors, demonstrated notably greater accuracy than a more traditional probabilistic approach without the adaptation of the algorithm to the data that the traditional probabilistic approach usually requires. Health IT policymakers, including the Office of the National Coordinator for Health Information Technology (ONC), should explore strategies to expand the evidence base for real-world matching system performance, given the need for an evidence-based patient identity strategy.
dc.eprint.versionFinal published version
dc.identifier.citationGrannis SJ, Williams JL, Kasthuri S, Murray M, Xu H. Evaluation of real-world referential and probabilistic patient matching to advance patient identification strategy. J Am Med Inform Assoc. 2022;29(8):1409-1415. doi:10.1093/jamia/ocac068
dc.identifier.urihttps://hdl.handle.net/1805/34653
dc.language.isoen_US
dc.publisherOxford University Press
dc.relation.isversionof10.1093/jamia/ocac068
dc.relation.journalJournal of the American Medical Informatics Association
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourcePMC
dc.subjectHealth IT policy
dc.subjectIdentity management
dc.subjectPatient identification
dc.subjectPatient matching
dc.subjectRecord linkage
dc.titleEvaluation of real-world referential and probabilistic patient matching to advance patient identification strategy
dc.typeArticle
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