Network Functional Connectivity Underlying Dissociable Cognitive and Affective Components of Empathy in Adolescence

dc.contributor.authorWinters, Drew E.
dc.contributor.authorPruitt, Patrick J.
dc.contributor.authorFukui, Sadaaki
dc.contributor.authorCyders, Melissa A.
dc.contributor.authorPierce, Barbara J.
dc.contributor.authorLay, Kathy
dc.contributor.authorDamoiseaux, Jessica S.
dc.date.accessioned2023-12-07T09:45:09Z
dc.date.available2023-12-07T09:45:09Z
dc.date.issued2021
dc.description.abstractEmpathy, the capacity to understand and share others' emotions, can occur through cognitive and affective components. These components are different conceptually, behaviorally, and in the brain. Neuroimaging task-based research in adolescents and adults document that cognitive empathy associates with the default mode and frontoparietal networks, whereas regions of the salience network underlie affective empathy. However, cognitive empathy is slower to mature than affective empathy and the extant literature reveals considerable developmental differences between adolescent and adult brains within and between these three networks. We extend previous work by examining empathy's association with functional connectivity within and between these networks in adolescents. Participants (n = 84, aged 13-17; 46.4% female) underwent resting state fMRI and completed self-report measures (Interpersonal Reactivity Index) for empathy as part of a larger Nathan-Kline Institute study. Regression analyses revealed adolescents reporting higher cognitive empathy had higher within DMN connectivity. Post hoc analysis revealed cognitive empathy's association within DMN connectivity is independent of affective empathy or empathy in general; and this association is driven by positive pairwise connections between the bilateral angular gyri and medial prefrontal cortex. These results suggest introspective cognitive processes related to the DMN are specifically important for cognitive empathy in adolescence.
dc.identifier.citationWinters DE, Pruitt PJ, Fukui S, et al. Network functional connectivity underlying dissociable cognitive and affective components of empathy in adolescence. Neuropsychologia. 2021;156:107832. doi:10.1016/j.neuropsychologia.2021.107832
dc.identifier.urihttps://hdl.handle.net/1805/37294
dc.language.isoen_US
dc.publisherElsevier
dc.relation.isversionof10.1016/j.neuropsychologia.2021.107832
dc.subjectAdolescence
dc.subjectAffective empathy
dc.subjectCognitive empathy
dc.subjectFunctional connectivity
dc.titleNetwork Functional Connectivity Underlying Dissociable Cognitive and Affective Components of Empathy in Adolescence
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Winters2021Network-PMC.pdf
Size:
731.4 KB
Format:
Adobe Portable Document Format
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.99 KB
Format:
Item-specific license agreed upon to submission
Description:
Collections